Structural brain abnormalities associated with preclinical cognitive impairment in Idiopathic Parkinson’s Disease.
Objective: Using the Progressive Parkinson’s Initiative (PPMI) data, clinical and structural differences between individuals destined to develop PD cognitive impairment was defined. Background: Cognitive dysfunction…Extended “Timed Up and Go”: A Clinical Indicator of Cognitive State in Parkinson’s Disease?
Objective: To evaluate an extended Timed Up and Go (extended-TUG) as a potential holistic indicator of Parkinson’s disease; hypothesised to correlate closely with disease severity…Synaptic biomarkers for cognitive decline in Lewy body dementias and Alzheimer’s disease. A mass spectrometry approach
Objective: The aim of our study is to understand the role of synaptic dysfunction in cognitive decline by comparing the whole proteome of Parkinson's disease…Association or causation? Orthostatic hypotension and cognitive impairment in α-synucleinopathies: A systematic review
Objective: To systematically review the literature for evidence of an association between orthostatic hypotension (OH) and cognitive impairment (CI) in α-synucleinopathies and to discuss possible…Apolipoprotein E genotypes in Brazilian patients with Parkinson’s disease and their correlation with cognitive performance assessed by MoCA
Objective: Analysing the relationship between the polymorphisms of ApoE gene and cognitive performance of patients with Parkinson's disease. Background: Cognitive impairment is a common clinical…Treatment with the use of the PD-specific scales for patients suffering from subcortical Parkinsonian dementia
Objective: Aim of this study was to identify the degree of cognitive dysfunction in patients with subcortical Parkinsonian dementia, during the neuroprotective therapy. Background: Parkinson's…α-synuclein in peripheral organs decreases in Lewy body disease complicated by Alzheimer’s disease
Objective: To examine whether the degree of α-synuclein (α-Syn) in the peripheral organs of patients with Lewy body disease (LBD: Parkinson's disease, dementia with Lewy…Clusterin CSF levels in differential diagnosis of neurodegenerative disorders
Objective: To find a specific in vivo marker to improve a differential diagnosis between Parkinson´s disease and atypical Parkinsonian syndromes, especially early in the course…Three cases of neuronal intranuclear inclusion disease (NIID)
Objective: Here, we present three NIID cases. One of them, autopsy was performed. Background: Neuronal intranuclear inclusion disease (NIID)(OMIM 603472) is a neurodegenerative disorder characterized…Allele specificity in neurodegenerative olfactory dysfunction
Objective: Assess olfactory dysfunction in carriers of the p.N279K and p.P301L MAPT mutations, which cause FTDP-17, to understand how genotypic differences contribute to the severity…
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