Comparative Grey and White Matter Tau Pathology in LBD and PSP using Digital Histologic Measurements
Objective: To compare the regional distribution of cortical tau pathology between Lewy body disorders (LBD: Parkinson’s disease and dementia with Lewy bodies (DLB)) and progressive…Synaptic function in Parkinson’s disease associated with GBA mutations
Objective: To investigate the pathological substrate of impaired cognition in Parkinson’s disease (PD) associated with glucocerebrosidase (GBA) mutation. Background: Mutations in glucocerebrosidase gene (GBA), originally…The effect of coexistent neurodegenerative disorders on the clinical features of idiopathic normal pressure hydrocephalus
Objective: To determine the prevalence of neurodegenerative disorders in idiopathic normal pressure hydrocephalus (iNPH) and their effects on the clinical features of iNPH. Background: To…Biomarkers of the Level of Cognitive Impairment (CI) in patients with Parkinson’s Disease (PD): MRS study
Objective: The concentrations of NAA, Cr, mIns, and Glx are identified as putative neurochemical markers of CI in patients with PD. Background: On the basis…Using Quantitative Susceptibility Mapping to Predict Dementia in Parkinson’s Disease
Objective: To investigate how brain iron deposition relates to visual function and dementia risk in Parkinson’s Disease (PD). Background: Oxidative stress due to brain iron…Alpha-synuclein expression and cytokine profile in blood of patients with Lewy body dementias
Objective: To examine alpha-synuclein expression in CD45+ and cytokine levels in blood of patients with dementia with Lewy bodies (DLB), Parkinson's disease dementia (PDD). Background:…DBS for Parkinson-Dementia syndrome: Stimulation of both Globus Pallidus internus & the Nucleus Basalis of Meynert using the same electrode lead
Objective: The study proposed a new Deep Brain Stimulation (DBS) approach in Parkinson´s disease (PD): the Globus pallidus pars interna (GPi) + Nucleus Basalis of…Cognitive impairment in Parkinson’s Disease: A cross-sectional association study
Objective: To characterize the presence and clinical presentation of PD-MCI and PDD in patients with idiopathic PD, examining motor and non-motor features and determining factors…Combined STN and NBM DBS in PD and mild to moderate Parkinson’s dementia
Objective: While deep brain stimulation (DBS) of the subthalamic nucleus (STN) alleviates Parkinson"s Disease(PD) related motor symptoms, to date PD dementia (PDD) patients are excluded…The influence of baseline body mass index on cognitive decline in Parkinson’s disease
Objective: The aim of this study is to know whether the baseline BMI is associated with cognitive decline and future development of dementia. Background: Alterations…
