Lewy body disease clinical subgroups present similar disease progression rates
Objective: To characterize LBD clinical subgroups and identify possible differences in disease progression. Background: Patients with Lewy body disease (LBD) present a wide variety of…The East London Parkinson Disease Project – engaging a diverse population in research
Objective: The objective of this study was to engage a diverse group of people with Parkinson disease (PwP) from East London and build a research…Plasma Alzheimer’s disease biomarkers and cognitive progression in Parkinson’s disease
Objective: To evaluate the relationship between plasma Alzheimer's disease biomarkers and cognitive progression in Parkinson's disease Background: Plasma phosphorylated tau (ptau) isoforms have been recently…A Phase 2 Randomized Controlled Trial Repurposing Ambroxol as a Disease Modifying Treatment for Parkinson’s Disease Dementia.
Objective: Currently there are no disease-treatments for Synucleinopathies including Parkinson’s disease dementia (PDD). Our objective is to use Ambroxol to target GBA/Glucocerebrosidase to treat PDD.…Exploring the Potential Anti-dementia Roles of Selected Herbal Anti-inflammatory Remedies in Parkinson’s Disease: Hopes and Challenges
Objective: To evaluate anti-dementia properties of the selected herbal anti-inflammatory remedies Background: Parkinson’s disease (PD) is the most common age-related neurodegenerative disease after Alzheimer’s disease.…Early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia: A Population-based Study (2010-2015).
Objective: To examine the incidence, clinical features, and survival of early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia (DLB/PDD) (≤55 years of age) in…Quantitative method for designing appropriate longitudinal follow-up frequency with application to Parkinson’s disease cognition research
Objective: To develop a quantitative method for designing appropriate longitudinal follow-up frequency. We demonstrate how to use this new method using a progression study of…Prevalence of Neuropsychiatric Symptoms in the Prodromal Stages of Dementia with Lewy Bodies and Parkinson’s Disease Dementia
Objective: Investigate neuropsychiatric features of prodromal stage dementia among individuals diagnosed with Lewy body disease. Background: There has been minimal investigation into the prodromal features…White Matter Changes and Early Cognitive Impairment in Parkinson’s Disease
Objective: Studying white matter changes in Parkinson's disease patients using diffusion tensor imaging; and its relation to cognition and motor symptoms impairment. Background: Cognitive dysfunction…Anxiety disorders are associated with verbal memory impairment in Parkinson’s disease
Objective: The present study aimed to investigate the association between anxiety disorders and memory impairment in Parkinson’s disease.The present study aimed to investigate the association…
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