MANF improves the MPP+/MPTP-induced Parkinson’s disease via improvement of mitochondrial function and inhibition of oxidative stress
Objective: This study aimed to investigate the therapeutic effect of mesencephalic astrocyte-derived neurotrophic factor (MANF) on the MPTP/MPP+-induced model of Parkinson's disease (PD) and the…Freezing of Gait in Parkinson’s Disease: Clinico-biochemical Observations
Objective: We aimed to compare motor and non-motor functions, 2D-spatiotemporal gait parameters and serum oxidative markers including catalase (CAT), superoxide dismutase (SOD) and malondialdehyde (MDA)…Protective effects of Mucuna pruriens seed on rat brain: A therapeutic potential drug for Parkinson’s disease
Objective: Objective of present study was evaluate neuroprotective and antiparkinson effects of Mp seed extract on Parkinsons brain of rats. Background: Parkinson’s disease (PD) is…Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s Disease
Objective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…Neuromodulatory properties of flavonoids from Persea americana Peel: Role in CNS redox homeostasis and neurobehavioral markers
Objective: Isolating flavonoids from Peel of Persea americana fruits & testing their effects on CNS redox homeostasis culminating in neurobehavioural amelioration among rats. Background: Cellular…Surface mechanised nano-formulation of naringenin as adenosine A2A receptor antagonist against in Neurological associated problem of Parkinson
Objective: In the current experimental study, we intended to develop Surface mechanized nano-formulation of naringenin (NG) as potent A(2A)AR antagonists against parkinson’s disease. Background: One…Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial
Objective: To investigate whether women and men with Parkinson's disease (PD) may differ in their biochemical and clinical responses to long-term treatment with urate-elevating inosine.…Curcumin improves cognitive function in rotenone-induced rat model of Parkinson’s disease (PD)
Objective: In this study, we aimed to investigate the neuroprotective effect of curcumin against rotenone-induced memory impairments in rat PD model. Background: In PD, oxidative…Rice bran extract against animal model of Huntington’s disease: Possible role of neurotransmitters
Objective: The present study has been designed to explore the effect of rice bran extract against 3-NP induced neurotoxicity in rats. Background: Huntington’s disease (HD)…Analysis of serum non-mercaptoalbumin in patients with Parkinson’s disease
Objective: It is well known that the oxidative stress might be associated with the pathomechanisms of Parkinson’s disease (PD). In this study, we assessed serum…
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