Gender-specific effects of uric acid on the development of freezing of gait in Parkinson’s disease
Objective: To investigate whether serum uric acid level is gender-specifically associated with the development of freezing of gait (FOG) in patients with de novo Parkinson’s…Beneficial and protective effects of Terminalia chebula in a murine model of Parkinson’s disease
Objective: Present study was designed to investigate whether Terminalia chebula (TC) extract would prevent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced neurotoxicity in male Wistar rats. Background: Parkinson's disease (PD)…High-throughput screening using a Drosophila model of Parkinson’s disease
Objective: To identify potential therapeutic compounds for Parkinson’s disease (PD) treatment by combining a phenotype-based high-throughput screening assay in PD model flies with a validation…Nrf2 pathway in patients with Parkinson’s disease
Objective: To demonstrate the activation of Nuclear factor erythroid-2-related factor 2 (Nrf2) pathway in PD patients. Background: Experimental data indicated the critical involvement of Nrf2…Serum non-mercaptalbumin as a potential biomarker in Parkinson’s disease and related disorders
Objective: To investigate the oxidized albumin ratio, which is the redox ratio of human non-mercaptalbumin (HNA) to serum albumin (HSA) (%HNA), as a biomarker in…Neuroprotective actions of red propolis extract and formononetin in a rat model of Parkinson’s disease
Objective: To evaluate the effects of the hydroalcoholic extract of red propolis (HERP) and one of its major compounds, formononetin (FN), against the motor symptoms…Quercetin administration abrogates the Parkinson’s disease (PD)-like motor and non-motor symptoms and attenuates the behavioral, neurochemical and biochemical deficits induced by rotenone toxicity in rats
Objective: The present study was carried out to investigate the preventive and therapeutic effects of quercetin (a flavonol) against rotenone-induced neurotoxicity. Background: Rotenone (pesticide) induced…Protective and therapeutic activity of Cinnamaldehyde in the mouse model of Parkinson’s disease
Objective: Objective of our study was to evaluate protective and therapeutic activity of Cinnamaldehyde in the mouse model of Parkinson’s disease. Background: Parkinson’s disease (PD),…Dietary Vitamin E as a protective factor for Parkinson’s Disease: a clinical and experimental study
Objective: To test if a higher dietary intake of Vitamin E might represent a protective factor in Parkinson’s disease (PD). Background: Effective disease-modifying treatments are…Effects of Glial Heme Oxygenase-1 on Neuronal Alpha-Synuclein in the GFAP.HMOX1 Mouse Model of Parkinson’s Disease
Objective: To determine whether astroglial HO-1 transduces environmental and endogenous stressors into patterns of neural damage which promote the toxicity of neuronal alpha-synuclein. Background: The…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.