Gait disturbance and olfactory dysfunction is associated with central cholinergic dysfunction in early Parkinson’s disease
Objective: We hypothesis that olfactory dysfunction, could be an independent predictor of gait disturbance in early PD. Background: The pathophysiology of gait disturbance is not fully…Progression to Parkinson’s disease in carriers of LRRK2 G2019S mutation: a 4-year prospective study with serial dopamine transporter imaging
Objective: To assess whether any of the biomarkers studied (UPDRS-III, SN echogenicity, UPSIT and DaT-SPECT) in a baseline evaluation of a cohort of LRRK2 G2019S asymptomatic…Clinical characteristics of Parkinson’s disease developed from essential tremor
Objective: The objective of this study is to compare the clinical characteristics of Parkinson’s disease developed from essential tremor (ET-PD) with the clinical characteristics of…Cardiac 123I-MIBG Scintigraphy, olfactory testing and transcranial sonography for differentiating between Parkinson’s disease and atypical parkinsonian syndromes during the early stage
Objective: To evaluate the utility of the combined use of cardiac metaiodobenzylguanidine (MIBG) scintigraphy, olfactory testing, and substantia nigra (SN) hyperechogenicity on transcranial sonography (TCS)…Validation of the Utility of Brief Smell Identification Test Simplified Chinese Version 2 in Chinese Parkinson’s disease
Objective: To validate the utility and efficiency of Brief Smell Identification Test Simplified Chinese Version 2 (B-SIT CV2) in Chinese Parkinson's disease patients and investigate…Olfactory Impairment in Parkinson’s Disease and White Matter Abnormalities in Central Olfactory Areas
Objective: To determine white matter abnormalities in PD patients with various degrees of olfactory impairment. Background: Neuroimaging results of PD brain based on diffusion tensor…Neuropsychological assessment in the Luxembourg Parkinson’s cohort (HELP-PD)
Objective: To report first results on the prevalence of cognitive non-motor symptoms in the Luxembourg Parkinson's cohort (HELP-PD). Background: HELP-PD aims to combine thorough assessment…Motor rigidity selectively associates with impaired odor identification in Parkinson’s disease
Objective: To investigate the relationship between impairments of the cardinal motor symptoms and odor identification deficits in Parkinson's disease (PD). Background: Although hyposmia has been…Allele specificity in neurodegenerative olfactory dysfunction
Objective: Assess olfactory dysfunction in carriers of the p.N279K and p.P301L MAPT mutations, which cause FTDP-17, to understand how genotypic differences contribute to the severity…Sniffing the diagnosis: Olfactory testing in neurodegenerative parkinsonism
Objective: To determine the diagnostic utility of olfactory testing in patients with neurodegenerative parkinsonism. Background: Olfactory dysfunction can be identified in the vast majority of…
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