Defining minimal clinically important differences in Huntington’s disease: An anchor-based approach
Objective: This study aims to estimate the longitudinal minimal clinically important difference (MCID) for HD-relevant, cognitive, motor, and functional outcome measures. We used the new…A prospective, controlled study of subthalamic stimulation in Parkinson’s disease: quality of life outcome at the 5-year follow-up
Objective: To compare the 60-months quality of life (QoL) effects of subthalamic stimulation (STN-DBS) to standard-of-care oral/transdermal medical therapy (MED) in Parkinson's disease (PD). Background:…Psychometric characteristics of the Neuropsychiatric Fluctuation Scale
Objective: To evaluate the psychometric properties of the Neuropsychiatric fluctuation scale (NFS) for Parkinson’s disease (PD). Background: Neuropsychiatric fluctuations (NpsyF) in PD are frequent and…Non-motor symptom characteristics in patients with essential tremor
Objective: The objective of this study was to evaluate non-motor symptoms in essential tremor (ET) and compare those to healthy controls (HCs). Background: ET is…Opicapone Improves Global Non-Motor Symptoms Burden in Parkinson´s Disease: An Open-label Prospective Study
Objective: The aim of this study was to analyze the effectiveness of opicapone on global non-motor symptoms (NMS) burden in Parkinson´s disease (PD). Background: Some…Blood biomarkers and their association with non-motor symptoms in early Parkinson’s Disease
Objective: To identify if baseline blood biomarkers are associated with non-motor symptoms in early PD. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with…Quality of life changes after subthalamic stimulation for Parkinson’s disease depend on nonmotor and motor symptoms clusters
Objective: To analyze quality of life (QoL) changes after subthalamic stimulation (STN-DBS) based on a short list of baseline nonmotor and motor symptoms in Parkinson’s…Mindfulness based program for newly diagnosed Parkinson’s patients.
Objective: To investigate the impact of 8-week course of Mindfulness based intervention program on motor and or non-motor symptoms of PD assessed by improvement in…The relationship of non-motor symptoms in Parkinson’s disease
Objective: Evaluation of non-motor symptoms in patients with Parkinson's disease, evaluation of the relationship of autonomic and neuropsychiatric disorders. Background: This work included a comprehensive…Liraglutide once daily versus placebo in Parkinson’s disease: a randomized, double-blind, placebo-controlled trial
Objective: To test safety and efficacy of the glucagon-like peptide 1 (GLP-1) agonist liraglutide in idiopathic Parkinson’s disease (PD). Background: Insulin resistance (IR) may play…
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