Movement disorders and it association with immunological causes: the key is in the movement
Objective: Observe the clinical and biochemical characteristics and the result of the treatment instituted in movement immune-mediated etiology. Background: Paraneoplastic autoimmune movement disorders are a…4-Chlorokynurenine inhibits L-Dopa-induced dyskinesias in non-human parkinsonian primates
Objective: This study investigated the antidyskinetic activity of 4-chlorokynurenine (AV-101) in parkinsonian monkeys with L-Dopa-induced dyskinesias. Background: The common treatment for Parkinson’s disease (PD) is L-Dopa…Rapidly progressive cognitive decline and hemi-dystonia due to anti-neuronal surface antibodies
Objective: To describe a case of marked asymmetric coarse tremor and dystonia in patient diagnosed with anti-NMDAR encephalitis. Background: Anti-NMDAR encephalitis has complex and heterogeneous…Brain neurotransmitters and neuropeptides alternations in Parkinson’s induced mouse models
Objective: Present study aimed to investigate the changes in brain neurotransmitters and neuropetides in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse models of PD. Background: Parkinson’s disease (PD), a…Neurorestorative effects of glycine transporter 1-inhibitor and D-Serine in a mouse model of nigrostriatal dopaminergic degeneration
Objective: We set out to evaluate potential neurorestorative effects of the GlyT1 inhibitor ACPPB vis-à-vis D-Serine in the intrastriatal 6-OHDA mouse model of Parkinson’s disease.…An extraordinary cause of psychosis: Anti-NMDA receptor encephalitis
Objective: Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis is an autoimmune encephalitis affecting predominantly young females. Background: It is characterized with neuropsychiatric symptoms, including personality changes, psychosis, autonomic…Effects of N-methyl-D-aspartate receptor antagonist in Parkinson’s disease with dementia
Objective: We conducted this longitudinal study to confirm the efficacy of memantine for PDD by analyzing comparative changes in regional cerebral blood flow (rCBF) and…Abnormal NMDA-related Electrophysiology in Parkinson Disease Dementia
Objective: Investigate mismatch negativity in Parkinson disease with dementia. Background: Parkinson’s disease with dementia (PDD) is an important cause of cognitive impairment in Parkinson’s disease…Modulation of CaMKIIa-NR2B interaction in levodopa-induced dyskinesia in 6-OHDA- lesioned Parkinson’s rats
Objective: In the present study, therefore, we examined the relationship between CaMKII and NR2B in levodopa-induced dyskinesia rats. Background: Long-term treatment with L-dopa leads to…The movement disorder associated with NMDAR-antibody encephalitis: An expert-rater video study
Objective: To use movement disorder (MD) expert analysis of phenomenology to provide a comprehensive evaluation of the MD associated with NMDA receptor-antibody encephalitis (NMDAR-AbE). Background:…