Somnolence as untoward stimulation effect in subthalamic deep brain stimulation (STN DBS) for Parkinson’s disease (PD)
Objective: Excessive daytime sleepiness is a relatively common feature in PD. However, it has not been reported as a side effect of STN DBS. We…Electric stimulation of the nucleus subthalamicus is able to modulate prepulse inhibition. A pilot study in Parkinson´s disease
Objective: To evaluate if prepulse inhibition (PPI) is influenced by electrical stimulation in the Nucleus subthalamicus (STN) of patients with Parkinson´s disease (PD). Background: PPI…VANTAGE trial: Three year outcomes of a prospective, multi-center trial evaluating deep brain stimulation with a new multiple-source, constant-current rechargeable system in Parkinson’s disease
Objective: The VANTAGE study assesses motor improvement in moderate-to-severe Parkinson's disease (PD) following bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) using a new, implantable,…Comparison of four DBS lead designs under voltage and current operating modes based on patient specific simulations
Objective: To quantitatively compare the spatial extension of the electric field generated by four different lead designs operated under voltage and current modes. Background: Conventional…DIRECT DBS: A prospective, multi-center clinical trial with blinding for a directional DBS lead
Objective: DIRECT DBS is an exploratory study which will investigate the effects of subthalamic deep brain stimulation (DBS) using directional DBS leads with current steering…Effect of bilateral subthalamic nuclei deep brain stimulation on impulse control disorders in PD
Objective: To study the effects of bilateral subthalamic nuclei stimulation on impulse control disorders(ICDs) in Parkinson's disease (PD). Background: Impulse control disorders(ICDs) cause significant morbidity…Changes of speech after neurostimulation for Parkinson’s disease with early fluctuations: A 2-years randomized controlled trial (earlystim-speech)
Objective: To assess the effect of subthalamic deep brain stimulation (STN-DBS) on speech in Parkinson's disease patients with early fluctuations and dyskinesia. Background: The effect…Accuracy of intraoperative CT during DBS procedures: Comparison with postoperative MRI
Objective: To determine the accuracy of intraoperative CT (iCT) in localizing deep brain stimulation (DBS) electrodes by comparing this modality with postoperative magnetic resonance imaging…Sensor-based motor state detection in Parkinson’s disease to approach personalized therapy delivery
Objective: As primary objective, we acquire a data pool of medically-treated PD patients with motor fluctuations to determine the sensitivity and specificity of algorithms capable…DTI tractographic correlates of weight gain in Parkinson’s disease patients after STN DBS
Objective: To assess DTI connectivity patterns and correlations with weight gain in Parkinson's disease patients after STN DBS. Background: Weight gain is a well-known adverse…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.