DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Intra-visit Impedance Changes
Objective: To evaluate impedance changes throughout the course of a programming visit as a part of a larger directional lead exploration study. Background: Historically, DBS…Prefrontal cortical stimulation to treat anxiety and depression in Parkinson’s disease
Objective: The aims of this study are 1) to study the neurophysiology underlying anxiety and depression in PD patients, and 2) to determine whether cortical…DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Therapeutic Windows with Directional Stimulation
Objective: To evaluate changes in therapeutic window values for changes in directional Deep Brain Stimulation (DBS) stimulation. Background: Historically, DBS systems have delivered stimulation using…CLOVER-DBS: A Prospective, Multi-center Clinical Study with Blinding to Evaluate a Closed Loop Programming Algorithm for Directional Leads Based on External Feedback
Objective: To assess the feasibility and efficacy of a novel closed-loop programming algorithm (CLPA) for directional lead deep brain stimulation (DBS) based on objective feedback…Five Year Outcomes of a Prospective, Multicenter Trial Evaluating Deep Brain Stimulation with a New Multiple Source, Constant Current Rechargeable System in Parkinson’s Disease
Objective: To evaluate the long term follow up of patients in the VANTAGE Study that employed a Deep Brain Stimulation (DBS) system with multiple independent…A wireless brain-spine interface alleviating gait deficits of non-human primates model of Parkinson’s disease
Objective: While levodopa and deep brain stimulation alleviate most of the symptoms associated with Parkinson's Disease (PD), axial gait disorders are less responsive to these…A comparative study on the alterations in the cortical excitability and central motor conduction time in spinocerebellar ataxias 1, 2, 3 and 12
Objective: This study evaluates and compares the RMT and CMCT in patients with genetically proven SCA1, SCA2, SCA3 and SCA12 using transcranial magnetic stimulation (TMS).…Cerebello-spinal stimulation in neurodegenerative ataxia: A randomized, double-blind, sham-controlled, crossover trial
Objective: The present study investigated whether a two-weeks' treatment with cerebellar anodal and spinal cathodal transcranial direct current stimulation (tDCS) could reduce symptoms in patients…A Registry of Real-World Outcomes Using Deep Brain Stimulation for the Treatment of Dystonia
Objective: The objective of this device registry entails collecting clinical outcomes, economic value and technical performance of a Deep Brain Stimulation (DBS) system capable of…Effect of multiple sessions of transcranial direct current stimulation in Writer’s cramp: Does it hold promise?
Objective: To assess the effect of 5 days of transcranial direct current stimulation (tDCS) on spiral drawing in Writer’s Cramp patients. Background: Writer’s cramp (WC)…
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