CLOVER-DBS: A Prospective, Multi-center Clinical Study with Blinding to Evaluate a Closed Loop Programming Algorithm for Directional Leads Based on External Feedback
Objective: To assess the feasibility and efficacy of a novel closed-loop programming algorithm (CLPA) for directional lead deep brain stimulation (DBS) based on objective feedback…Five Year Outcomes of a Prospective, Multicenter Trial Evaluating Deep Brain Stimulation with a New Multiple Source, Constant Current Rechargeable System in Parkinson’s Disease
Objective: To evaluate the long term follow up of patients in the VANTAGE Study that employed a Deep Brain Stimulation (DBS) system with multiple independent…A wireless brain-spine interface alleviating gait deficits of non-human primates model of Parkinson’s disease
Objective: While levodopa and deep brain stimulation alleviate most of the symptoms associated with Parkinson's Disease (PD), axial gait disorders are less responsive to these…A comparative study on the alterations in the cortical excitability and central motor conduction time in spinocerebellar ataxias 1, 2, 3 and 12
Objective: This study evaluates and compares the RMT and CMCT in patients with genetically proven SCA1, SCA2, SCA3 and SCA12 using transcranial magnetic stimulation (TMS).…Cerebello-spinal stimulation in neurodegenerative ataxia: A randomized, double-blind, sham-controlled, crossover trial
Objective: The present study investigated whether a two-weeks' treatment with cerebellar anodal and spinal cathodal transcranial direct current stimulation (tDCS) could reduce symptoms in patients…A Registry of Real-World Outcomes Using Deep Brain Stimulation for the Treatment of Dystonia
Objective: The objective of this device registry entails collecting clinical outcomes, economic value and technical performance of a Deep Brain Stimulation (DBS) system capable of…Effect of multiple sessions of transcranial direct current stimulation in Writer’s cramp: Does it hold promise?
Objective: To assess the effect of 5 days of transcranial direct current stimulation (tDCS) on spiral drawing in Writer’s Cramp patients. Background: Writer’s cramp (WC)…Does the degree of improvement after deep brain stimulation surgery for Parkinson’s disease (PD) meet the patient’s expectations?
Objective: This research is a quantitative, exploratory study, which aims to identify the symptoms that patients expect to improve with Deep brain stimulation (DBS) and…Feasibility and Efficacy of Brainstem Modulation Therapy for the Management of Parkinson’s Disease
Objective: To evaluate the feasibility and potential efficacy of a software-controlled, solid-state caloric vestibular stimulation (CVS)-mediated brainstem modulation device for the treatment of non-motor and…Safety and efficacy of high definition tDCS for proprioception and balance in Parkinson’s disease: A pilot randomised trial
Objective: To determine: 1. Is HD-tDCS safe and well-tolerated in PD? 2. Does combined HD-tDCS and physical exercise improve proprioception and balance in PD? Background:…
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