Comparison between clinical and kinematic assessment of bradykinesia
Objective: To compare the clinical and kinematic assessment of bradykinesia (movement slowness). Background: Bradykinesia may be present not only in Parkinson’s disease (PD), but also…Early experience using real-world monitoring to inform Parkinson’s management
Objective: To explore the utility of remote patient monitoring, using a combination of brain sensing and objective outcome measurement, in the management of Parkinson’s disease…Subthalamic tremor-related oscillatory neurons play a role in the generation of Parkinson’s tremor
Objective: To explore whether subthalamic tremor-related oscillatory neurons is involved in the generation of Parkinson’s tremor. Background: Both the basal ganglia and cerebello-thalamo-cortical circuits appear…Task-Specific Dystonia is a predominant disorder of Top-Down Sensorimotor integration
Objective: In this study we investigate two neurophysiologic variables testing for central-peripheral and peripheral-central mechanisms of SM integration in a cohort of TSD to evaluate…Pilot study to investigate the use of in-clinic sensing to identify optimal stimulation parameters for deep brain stimulation therapy in Parkinson’s disease
Objective: Compare the use of in-clinic sensing functionality and standard of care monopolar review for identifying optimal settings of a deep brain stimulation (DBS) in…Shared molecular genetic factors influence brain morphometry and Parkinson’s disease risk
Objective: To explore the genetic overlap and identify shared genomic regions between brain morphometry and Parkinson’s disease (PD) risk. Background: PD is a genetically complex…Sigma Absolute Spectral Power is Associated with Depression in Parkinson’s Disease
Objective: This cross-sectional study investigated the relationship between depression and sigma absolute spectral power (9-15 Hz) in the frequency range of sleep spindles during non-rapid…Effect of clinical levodopa medication cycle on subthalamic beta band power during therapeutic deep brain stimulation in Parkinson’s disease
Objective: To characterize the effect of levodopa medication cycle on subthalamic nucleus (STN) local field potential (LFP) beta-band power in Parkinson’s disease (PD) in the…Towards a Machine Learning Based Classification System for Hyperkinetic Movement Disorders: Generating a Neurophysiological Feature Set
Objective: Generating a set of significant neurophysiological features to build a machine learning based diagnostic system for hyperkinetic movement disorders. Background: Hyperkinetic movement disorders cause…Determination of metabotropic glutamate receptor 2/3 distribution with [3H]-LY-341,495 in Parkinson’s disease patients with visual hallucinations
Objective: To determine the distribution and levels of metabotropic glutamate 2/3 (mGlu2/3) receptors in brain tissue from patients with Parkinson’s disease (PD) with visual hallucinations (VHs).…
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