The Pull Test in healthy subjects and Parkinson´s disease: quantitative pull-force measure, postugraphic and electromyographic analysis
Objective: To study and compare in healthy subjects and patients with Parkinson´s disease (PD) the destabilizing force needed to reach the limit of stability (LoS), the displacements of…Intracortical plasticity is preserved in de novo Parkinson’s disease: a tSMS study.
Objective: To test the intracortical plasticity of motor cortex in treatment-naïve (de novo) patients with Parkinson’s disease (PD), by means of transcranial static magnetic field…Beta oscillatory changes during practice and retention of motor skills in healthy subjects and patients with PD
Objective: The objective is to define the relationship between increase in beta oscillatory changes with practice and retention of motor skills in normal healthy subject…Efficient control of dopamine neuron physiology for rescuing disease phenotypes
Objective: Dopamine neurons (DAs) of the substantia nigra degenerate in Parkinson's disease and are disrupted in Huntington's disease. Here we propose single cell computational modeling…Objective gait parameters as a noninvasive biomarker for freezing of gait in Parkinson’s disease patients
Objective: To determine if steady-state gait parameters in Parkinson disease (PD) patients could serve as a predictive biomarker for freezing of gait (FOG). Background: FOG…The AppTUG : a new application for analyzing the Timed Up and Go task in patients with neurological disorders
Objective: To perform an initial validation of a newly developed smartphone-based Timed Up & Go (TUG) application (AppTUG), by comparing its measurements to the stopwatch-measured…Floor square size predicts step count of 360° turns in PD patients with freezing
Objective: To determine the effect of floor square size on turning behavior in patients with PD. Background: Turning has been repeatedly shown to be the…Diffusion tensor imaging in Parkinson’s disease: Review and meta-analysis with clinical considerations and neuroimaring parameters
Objective: (1) To synthesize brain white matter changes with diffusion tensor imaging (DTI) in Parkinson's disease (PD); and (2) to study correlations of these changes…Subthalamic nucleus activity during virtual reality provoked lower limb freezing in a patient with Parkinson’s disease and freezing of gait
Objective: Record subthalamic nucleus activity in a Parkinson's disease patient with gait freezing while they perform a virtual reality walking task during DBS surgery. Background:…Movement related beta oscillatory activity during self-paced wrist movement in the human subthalamic nucleus
Objective: To explore voluntary movement related neuronal activity in the subthalamic nucleus in patients with Parkinson's disease (PD). Background: How the human basal ganglia processes…
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