Pain Syndromes in Parkinsonism Depending on the Form Disease
Objective: To study of pain syndromes in various forms of Parkinsonism. Background: Pain can occur in the premotor stage of Parkinson's disease, motor signs are…Characterization of pallidal neuronal activity in X-linked dystonia-parkinsonism – a model disease for compartment degeneration in the striatum
Objective: Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is a highly effective symptomatic therapy for dystonia in X-linked dystonia-parkinsonism (XDP). A deeper…An agent-based model replicates the pathogenic spread of alpha-synuclein in mice
Objective: To investigate the ability of a susceptible-infected-removed (SIR) agent-based model to predict the pathogenic spread of alpha-synuclein fibrils after injection in mice. Background: Parkinson’s…Detection of impaired finger dexterity by objective keyboard typing test in Parkinson’s Disease: A feasibility study
Objective: To objectively evaluate finger dexterity in Parkinson’s disease (PD) patients by keyboard typing test. Background: Impaired motor dexterity is a type of bradykinesia which…Does lesion localisation predict tremor characteristics in patients with focal cerebellar lesion?
Objective: To determine if lesion localisation correlates with tremor characteristics in patients with focal cerebellar lesion. Background: It is a clinical experience that acute lesions…A cortical signature of motor response to dopaminergic therapy in Parkinson’s disease
Objective: To investigate whether cortical oscillations involved in sensorimotor processes might predict motor symptom response to dopaminergic treatment (MSRD) in Parkinson’s disease (PD). Background: MSRD…Neurophysiologic characterization of Re-emergent tremor (RET) in Parkinson’s disease
Objective: To investigate: 1) the contribution of primary motor cortex (M1) to the generation of re-emergent tremor (RET) and rest tremor by measuring the Cortico-muscular…Approaches to assessing of disorders of voluntary posture control in patients with Parkinson’s disease
Objective: To assess disorders of VPC using the characteristics of the speed of voluntary movements in patients with PD. Background: At the advanced stage of…Botulinum toxin injections reduce the symptoms of dystonic tremor and improve sensorimotor function for hand dexterity
Objective: To assess improvement in hand function following therapy with botulinum toxin in patients with dystonic tremor (DT). Background: Treatment of dystonic tremor (DT) with…Prefrontal cortex high beta power correlates with the severity of anxiety and depression in Parkinson’s disease patients
Objective: To investigate the neural correlates of anxiety and depression in PD patients and to develop a novel neurostimulation therapy for these non-motor symptoms. Background:…
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