Spinal Excitability and Plasticity in Hereditary Spastic Paraparesis: A Neurophysiological Study
Objective: To investigate spinal excitability and plasticity in patients with pure hereditary spastic paraparesis (HSP). Background: Pure HSP (SPG4) is a neurodegenerative disorder characterized by…A new fully implantable Adaptive Deep Brain Stimulation system tested for the first time in patients with Parkinson’s Disease
Objective: This multicenter double-blind crossover study has been designed to evaluate the safety and efficacy of adaptive Deep Brain Stimulation delivered through an innovative IPG…A prospective study of Parkinson’s disease dementia – defining neuropsychological features
Objective: To identify neuropsychological predictors of conversion to dementia (PDD) in our cohort of Parkinson’s disease (PD) patients. Background: The heterogeneity of PD cognitive disorders…Paradoxical cerebral hyperperfusion in Parkinson’s disease with orthostatic hypotension
Objective: This study manipulated the imaging modality to illustrate the physiology of cerebral flow with OH in PD (PD+OH). Background: Orthostatic hypotension (OH) may antedate…Patient classification for adaptive deep brain stimulation
Objective: To explore a control theory modeling framework to classify which Parkinson’s disease patients may benefit from adaptive deep brain stimulation. Background: Deep brain stimulation…Ballistic single-joint arm movements in levodopa-induced dyskinesias in Parkinson´s disease.
Objective: To design a pilot study to analyze ballistic movements in Parkinson's disease patients with levodopa-induced dyskinesia. Background: Ballistic movements are characterized by an electromyographic…High intensity exercise improves Sleep EEG Delta Power in Parkinson’s Disease
Objective: This novel study tests the hypothesis that 16 weeks of high-intensity exercise rehabilitation combining resistance training plus body-weight interval training, compared with a sleep…Identifying de novo Parkinson’s disease with optical coherence tomography of the retina: A machine learning classification approach
Objective: To identify and classify de novo Parkinson’s disease patients compared to healthy controls (HC). Background: PD patients experience visual symptoms and retinal degeneration. Studies…Quantitative study of the effect of thalamotomy by MRgFUS in the different types and locations of tremor in the contralateral upper limb
Objective: To quantify the improvement of different types of tremor in upper limb using the spectrum of accelerometer signal in patients treated with unilateral lesions…Prefrontal cortical activity and the control of walking in people with freezing of gait
Objective: To investigate the influence of freezing of gait (FoG) on automaticity of walking in people with Parkinson’s disease (PD). Background: A hallmark of healthy…
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