Neuromelamin-MRI in patients with Pure Autonomic Failure
Objective: To assess the utility of neuromelanin-MRI (NM-MRI) methods in a prodromal alpha-synuclein disorder, Pure Autonomic Failure (PAF). Background: PAF is a peripheral alpha-synucleinopathy (AS)…Depressive Symptoms are Associated with Lower Locus Coeruleus Volumes in Parkinson’s disease
Objective: To assess locus coeruleus volumes in Parkinson's disease patients with depressive symptoms. Background: Depression associated with Parkinson disease (PD) has a different symptom profile…Neuromelanin Imaging and Midbrain Volumetry in Progressive Supranuclear Palsy and Parkinson’s Disease
Objective: Using neuromelanin-sensitive magnetic resonance imaging (NM-MRI) and midbrain volumetry, we analyzed differences and relationships between nigral degeneration and midbrain atrophy in PSP and PD…Longitudinal changes in Neuromelanin MRI Signal in Parkinson’s Disease
Objective: To examine the longitudinal changes in neuromelanin (NM) MRI signal in the substantia nigra (SN) in Parkinson’s disease (PD). Background: PD is characterized by…Quantitative analysis of DaT uptake and neuromelanin MR contrast in patients with Parkinson’s disease and healthy controls
Objective: To examined quantitative measures of neuromelanin (NM) MRI and DaT-SPECT imaging of the SN and striatum to distinguish PD patients from healthy control subjects…Semi-automated segmentation and quantification of the substantia nigra depigmentation in Parkinson’s disease – a multicentre case control MRI study in 284 participants
Objective: To provide a semi-automated segmentation and quantification method of the changes in the substantia nigra (SN) in Parkinson’s disease (PD) using neuromelanin (NM)-sensitive MRI…Neuromelanin Magnetic Resonance Imaging of the Substatia Nigra in LRRK2 -related Parkinson’s disease
Objective: Our study aimed to evaluate neuromelanin-Magnetic Resonance signal changes in PD patients carrying a LRRK2 mutation. Background: Specific magnetic resonance (MR) sequences are able to…[18F]-AV-1451 binding to neuromelanin in the substantia nigra in PD and PSP
Objective: This study was designed to investigate the binding of [18F]-AV-1451 to neuromelanin in parkinsonisms. Uptake in the substantia nigra of Parkinson’s disease (PD) and…Substantia nigra area evaluated by neuromelanin-sensitive MRI as an imaging biomarker of disease progression in Parkinson’s disease
Objective: to investigate the pattern of substantia nigra - neuromelanin (SN-NM) area loss and contrast ratio (CR) intensity changes in late-stage Parkinson’s disease (LSPD) patients,…Prognostic factors of motor symptoms in Parkinson’s disease using neuromelanin imaging and the relationship with (123)I-FP-CIT-SPECT
Objective: This study aimed to examine the relationship between findings of neuromelanin sensitive MRI findings and motor complications. We also examined the correlation of findings…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.