Early predictors of Parkinson’s disease and prognosis in relatives
Objective: To study early clinical and biochemical markers of Parkinson's disease (PD) in relatives of Uzbek nationality. Background: Parkinson's disease is a neurodegenerative hereditary disease…Parkinson’s Foundation Physical Therapy Faculty Program Evaluation
Objective: In 2016, the Parkinson’s Foundation partnered with clinical and research experts to implement a training program for physical therapy (PT) faculty who want to…Contribution of coding/noncoding variants in NUS1 to late-onset sporadic Parkinson’s disease
Objective: Here, we designed a case-control study to analyze WGS variants in NUS1 coding regions and NUS1 related non-coding regions to investigate the relative contribution…Hereditary and geneological aspects of Parkinson’s disease and essential tremor in people of Uzbek nationality
Objective: To study the genealogic features of Parkinson’s disease and essential tremor in people of Uzbek nationality. Background: Parkinson's disease (PD) and essential tremor (ET)…Detection of genetic modifiers in PRKN
Objective: In this study, we investigate the Hypothesis 1 using Next-generation sequencing (NGS). Background: In 1998, we reported homozygous mutations of PRKN as the causative…Differential effects of stem cell therapy in adult and middle-aged Parkinsonian mice
Objective: To perform an in-depth analysis of the effects of transplanting neural stems cells in Parkinsonian mice. Background: Parkinson´s disease (PD) is the second most…Dopaminergic Neuroregeneration in the Diencephalon of 6-OHDA-Lesioned Adult Zebrafish-Based Parkinson’s Disease Model
Objective: This study established a 6-OHDA-lesioned adult zebrafish-based PD model and investigated the neuroregenerative processes of diencephalic dopaminergic neurons (DpN). Background: Studies on endogenous neuroregeneration…Increased vesicular monoamine transporter alleviate MPTP-induced impairment of neurogenesis
Objective: In this study, we employed vesicular monoamine transporter 2–overexpressing mice (VMAT2-HI) to investigate the influence of increased vesicular storage of catacholamines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced…Gastrointestinal disorders in various forms of parkinsonism
Objective: To examine the types of gastrointestinal disorders in parkinsonism, depending on the form of the disease. Background: One of the non-motor autonomic disorders of…Dopaminergic stem cells reside in the rostral migratory stream
Objective: To analyze if the adult rostral migratory stream (RMS) harbors neural stem cells with the potential to create dopaminergic neurons for the olfactory bulb…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.