Expanding the Spectrum of Autosomal Recessive Genes Responsible for Parkinson’s Disease in the Chinese Population
Objective: We aimed to identify novel candidate autosomal recessive (AR) genes combining whole-exome sequencing (WES) and long-read sequencing data (LRS) in autosomal recessive Parkinson’s disease (AR-PD) families and sporadic early-onset…Latent Genetic Architecture of Parkinson’s Disease Risk factors and Comorbidities
Objective: To comprehensively investigate the genetic relationship between Parkinson’s disease (PD), its risk factors, and comorbidities by constructing a factor model of the shared genetic…The Black and African American Connections to Parkinson’s Disease Study
Objective: BLAAC PD is a multi-center study recruiting Black and African American individuals with Parkinson’s Disease (PD) and healthy controls. The ultimate goal is to…Adult hippocampal neurogenesis-associated memory performance in people with Parkinson’s disease with and without cognitive impairment
Objective: To evaluate the role of adult hippocampal neurogenesis (AHN)-associated memory measures to the cognitive performance of people with Parkinson’s disease (PwP) with or without…Cognitive Function in Late-life and Parkinson’s Disease Neuropathology at Death
Objective: To examine the association between cognitive function in late-life and Parkinson’s disease (PD) neuropathology at death, including 1) neuron loss in the locus coeruleus…Evolution of biochemical and clinical signature of GBA-related Parkinson’s Disease: a 2-year longitudinal study
Objective: To evaluate peripheral biochemical markers as well as clinical features of GBA-related Parkinson’s Disease (GBA-PD) subjects over a 2-year follow-up in comparison with NM-PD…HAB-C murine model present reactive adult neurogenesis and astrogliosis in adult brain
Objective: To analyze the adult neurogenic response to a neurodegenerative process due to H-ABC tubulinopathy. Background: H-ABC is a neurodegenerative disease caused by mutations in…Correlation between H-ABC and thyroid hormones signaling in the process of adult neurogenesis
Objective: To analyze a possible correlation between the TH signaling and cellular fate of adult neural stem cells on taiep rats. Background: H-ABC is a…Parkinson’s Foundation Physical Therapy Faculty Program Evaluation
Objective: In 2016, the Parkinson’s Foundation partnered with clinical and research experts to implement a training program for physical therapy (PT) faculty who want to…Contribution of coding/noncoding variants in NUS1 to late-onset sporadic Parkinson’s disease
Objective: Here, we designed a case-control study to analyze WGS variants in NUS1 coding regions and NUS1 related non-coding regions to investigate the relative contribution…