Expanding the Spectrum of Autosomal Recessive Genes Responsible for Parkinson’s Disease in the Chinese Population
Objective: We aimed to identify novel candidate autosomal recessive (AR) genes combining whole-exome sequencing (WES) and long-read sequencing data (LRS) in autosomal recessive Parkinson’s disease (AR-PD) families and sporadic early-onset…Latent Genetic Architecture of Parkinson’s Disease Risk factors and Comorbidities
Objective: To comprehensively investigate the genetic relationship between Parkinson’s disease (PD), its risk factors, and comorbidities by constructing a factor model of the shared genetic…The Black and African American Connections to Parkinson’s Disease Study
Objective: BLAAC PD is a multi-center study recruiting Black and African American individuals with Parkinson’s Disease (PD) and healthy controls. The ultimate goal is to…Adult hippocampal neurogenesis-associated memory performance in people with Parkinson’s disease with and without cognitive impairment
Objective: To evaluate the role of adult hippocampal neurogenesis (AHN)-associated memory measures to the cognitive performance of people with Parkinson’s disease (PwP) with or without…Cognitive Function in Late-life and Parkinson’s Disease Neuropathology at Death
Objective: To examine the association between cognitive function in late-life and Parkinson’s disease (PD) neuropathology at death, including 1) neuron loss in the locus coeruleus…Evolution of biochemical and clinical signature of GBA-related Parkinson’s Disease: a 2-year longitudinal study
Objective: To evaluate peripheral biochemical markers as well as clinical features of GBA-related Parkinson’s Disease (GBA-PD) subjects over a 2-year follow-up in comparison with NM-PD…HAB-C murine model present reactive adult neurogenesis and astrogliosis in adult brain
Objective: To analyze the adult neurogenic response to a neurodegenerative process due to H-ABC tubulinopathy. Background: H-ABC is a neurodegenerative disease caused by mutations in…Correlation between H-ABC and thyroid hormones signaling in the process of adult neurogenesis
Objective: To analyze a possible correlation between the TH signaling and cellular fate of adult neural stem cells on taiep rats. Background: H-ABC is a…NUS1 polymorphisms modify the risk and age at onset of Parkinson’s disease
Objective: In this study, using whole-exome sequencing (WES) and direct Sanger sequencing analysis, we investigated the common and low-frequency variants of NUS1 in two case-control…Association of Interleukin (IL)-2 and IL2RA gene polymorphisms with Parkinson’s disease in Taiwan
Objective: The purpose of this study is to investigate if interleukin 2 (IL-2) and interleukin 2 receptor alpha (IL2RA) genes are associated with Parkinson’s disease…