GCI-induced neurodegeneration and synucleinopathy in non-human primates
Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…Neuroinflammation and Myelin changes in MSA-P evaluated using Advanced Diffusion MRI and Myelin Sensitive Imaging Techniques
Objective: To determine more specific neuropathologies of the white matter in patients with multiple system atrophy-parkinsonian variant (MSA-P) using multi-shell diffusion magnetic resonance imaging (MRI)…CHCHD2 mRNA levels in erythrocyte are reduced in patients with multiple system atrophy
Objective: To investigate CHCHD2 mRNA expression of erythrocyte in patients with multiple system atrophy (MSA). Background: Coiled-coil-helix-coiledcoil-helix domain containing 2 (CHCHD2) are reported to be associate with…Multiple System Atrophy – perspectives in diagnosis?
Objective: The aim of this study was to study the role of perfusion single photon emission computed tomography (SPECT) in the examination of multiple system…Abnormal respiratory rate and patterns in MSA
Objective: To evaluate respiratory rate and patterns in patients with Multiple Systems Atrophy (MSA). Background: One of the primary clinical features of multiple system atrophy…Speculation on the timing of iron deposition in the putamen of patients with multiple system atrophy: multimodal MRI study
Objective: We sought to investigate the temporal pattern of iron deposition in the putamen of patients with multiple system atrophy (MSA) by calculating conditional probabilities…Unraveling biological processes implicated in MSA and PD by transcriptomic analysis
Objective: To find differential biological processes between synucleinopathies (MSA and PD). Background: Multiple system atrophy (MSA) is an oligodendroglial sinucleinopathy that is often misdiagnosed as…Differences in resting state fMRI distinguish multiple system atrophy and Parkinson disease
Objective: To investigate whether functional connectivity of the hypothalamus can distinguish multiple system atrophy from Parkinson disease. Background: Multiple system atrophy parkinsonian subtype (MSA-P) and…Abnormal metabolic brain network in multiple system atrophy and progressive supranuclear palsy: a replication on a new European cohort
Objective: To identify characteristic metabolic brain patterns specific for multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) in a new cohort of patients and…Increased lysosphingolipids levels in blood of patients with multiple system atrophy
Objective: To estimate activity of lysosomal enzymes and lysosphingolipids concentration in dry blood spot of patients with synuleinopathies: Parkinson’s disease (PD), dementia with Lewy bodies…