CHCHD2 mRNA levels in erythrocyte are reduced in patients with multiple system atrophy
Objective: To investigate CHCHD2 mRNA expression of erythrocyte in patients with multiple system atrophy (MSA). Background: Coiled-coil-helix-coiledcoil-helix domain containing 2 (CHCHD2) are reported to be associate with…Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study
Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…GCI-induced neurodegeneration and synucleinopathy in non-human primates
Objective: This study aimed at determining the potential to induce MSA pathology in non-human primates. Background: Aggregation of alpha-synuclein has been implicated in several neurodegenerative…Abnormal metabolic brain network in multiple system atrophy and progressive supranuclear palsy: a replication on a new European cohort
Objective: To identify characteristic metabolic brain patterns specific for multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) in a new cohort of patients and…Increased lysosphingolipids levels in blood of patients with multiple system atrophy
Objective: To estimate activity of lysosomal enzymes and lysosphingolipids concentration in dry blood spot of patients with synuleinopathies: Parkinson’s disease (PD), dementia with Lewy bodies…Hypothalamic functional connectivity correlates with autonomic symptom burden in patients with Multiple System Atrophy
Objective: To investigate the association between autonomic symptom burden and hypothalamic functional connectivity in patients with MSA. Background: Multiple system atrophy (MSA) is a progressive…Pain in patients with multiple system atrophy: a pain-related evoked potential study
Objective: The purpose of this study was to investigate the pathophysiology of pain in patients with multiple system atrophy (MSA). Background: MSA is an atypical…Vocal cords electromyography abnormalities in multiple system atrophy phenotypes: relevance for the pathophysiology of stridor
Objective: To define correlations between vocal cords electromyography (EMG) abnormalities and stridor in multiple system atrophy (MSA) phenotypes. Background: MSA is a rare α-synucleinopathy characterized…Widespread distribution and abundant accumulation of alpha-synuclein oligomers in multiple system atrophy brain
Objective: To examine the distribution of alpha-synuclein (αSyn) oligomers as an early pathological change in multiple system atrophy (MSA) brains. Background: Although severe neuronal loss…Multiple System Atrophy – perspectives in diagnosis?
Objective: The aim of this study was to study the role of perfusion single photon emission computed tomography (SPECT) in the examination of multiple system…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.