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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Multiple system atrophy(MSA): Etiology and Pathogenesis"

  • MDS Virtual Congress 2021

    Alteration of lysosomal enzymatic activities in patients with multiple system atrophy

    A. Bezrukova, K. Basharova, D. Bogdanova, K. Senkevich, A. Zhuravlev, E. Gracheva, I. Miliukhina, G. Baydakova, E. Zakharova, A. Emelyanov, S. Pchelina, T. Usenko (Gatchina, Russian Federation)

    Objective: To estimate whether alteration of lysosomal activities contributes to synucleinophaties pathogenesis. Background: Multiple system atrophy (MSA) belongs to a group of neurodegenerative disorders termed synucleinopathies, which also include Parkinson's disease (PD)…
  • MDS Virtual Congress 2021

    Plasma Short-Chain Fatty Acids Differences in Multiple System Atrophy from Parkinson’s Disease

    XQ. He, YW. Qian, SQ. Xu, Y. Zhang, CJ. Mo, XD. Yang, Q. Xiao (Shanghai, China)

    Objective: We aimed to investigate the plasma short-chain fatty acids (SCFAs) in multiple system atrophy (MSA) patients and to identify the potential differential diagnostic ability.…
  • MDS Virtual Congress 2021

    Mapping regional alpha-synuclein seeding capacity in Multiple System Atrophy

    I. Martinez-Valbuena, N. P. Visanji, A. Kim, S. Lee, S. Alshimemeri, R. So, A. Gao, J. C. Watts, A. Lang, G. G. Kovacs (Toronto, Canada)

    Objective: The objective of our work was to develop a novel high-throughput cell-free assay that allowed us to perform a comprehensive characterization of α-synuclein seeding…
  • MDS Virtual Congress 2020

    The relationship between MIBG myocardial scintigraphy and clinical factors in multiple system atrophy

    R. Yokoyama, R. Okuda, K. Seo, K. ota, H. Kawasaki, K. Kazushi, Y. Nakazato, I. MatunariI, N. Tamura, T. Yamamoto (Saitama, Japan)

    Objective: This study aimed to clarified the relationship between the degree of MIBG accumulation and clinical factors in patients with MSA. Background: 123I-MIBG myocardial scintigraphy considered to…
  • MDS Virtual Congress 2020

    Alpha-synuclein and Amyloid beta peptide 1-42 in Parkinson’s disease and parkinsonian plus syndrome cohorts

    G. Babu, M. Gupta, V. Paliwal (Lucknow, India)

    Objective: To evaluate the serum levels of α-synuclein (α-syn) and Amyloid β 1-42 (Aβ1-42) in the patients of Parkinson’s disease (PD), progressive supranuclear palsy (PSP)…
  • MDS Virtual Congress 2020

    Mass spectrometry-based proteomics brain analysis to distinguish between Parkinson syndromes

    A. Rajput, P. Chumala, B. Thompson, A. Rajput, G. Katselis (Saskatoon, SK, Canada)

    Objective: To address the gap existing during clinical diagnosis in differentiating among various forms of Parkinson syndrome (PS) by using mass spectrometry (MS)-based brain proteomics.…
  • MDS Virtual Congress 2020

    Detection of alpha-synuclein aggregation from submandibular and esophageal tissue of patients with synucleinopathies

    T. Yamasaki, T. Sudhakar, E. Ostrakhovitch, E. Song (Lexington, KY, USA)

    Objective: Utilize cyclic amplification methods to facilitate detection of aggregation prone forms of a-syn from submandibular or esophageal tissue of patients with syncleinopathies. Background: In…
  • MDS Virtual Congress 2020

    Quantitative evaluation of Multiple System Atorphy by triaxial accelerometers and 9-hole peg test

    S. Shirai, C. Sato, M. Matsushima, I. Yabe, H. Sasaki (Sapporo, Japan)

    Objective: We need a concise and responsive biomarker for multiple system atrophy (MSA). Background: In Japan, the majority of patients of MSA are of the…
  • MDS Virtual Congress 2020

    Serum neurofilament light chain differentiates early Parkinson’s disease from progressive supranuclear palsy-parkinsonism

    R. Yadav, P. Ramaswamy, P. Pal, R. Christopher (Bengaluru, India)

    Objective: To assess the value of serum neurofilament light chain (NFL) levels in differentiating parkinsonian syndromes. Background: The diagnosis of Parkinson’s disease (PD) mostly relies…
  • 2019 International Congress

    Serum MIR-96-5P and MIR-339-5P as a Potential Biomarker for Multiple System Atrophy and Parkinson’s Disease

    A. Vallelunga, T. Iannitti, S. Capece, G. Somma, G. Dati, P. Barone, W. Meissner, M. Pellecchia (Salerno, Italy)

    Objective: The aim of our study was to to determine if serum mir-96-5p and mir-339-5p can be used as biomarkers for early diagnosis of Parkinson’s…
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