Intraepidermal Nerve Fiber Density at Baseline Associates with One-year Clinical Disease Progression in Multiple System Atrophy
Objective: In a longitudinal manner explore possible diagnostic and prognostic properties of determining intraepidermal nerve fiber density (IENFD), by means of skin punch biopsy, in…Unsupervised Learning Approach for Pathology-Based Subtyping and Staging Multiple System Atrophy
Objective: To develop a classification and staging system for multiple system atrophy (MSA) using data-driven disease progression modeling. Background: MSA exhibits varying degrees of degeneration…Association Between Clinical Progression in Multiple System Atrophy and Brain Volume Changes Evaluated via Deep Learning Segmentation
Objective: Assess brain volume changes in patients with multiple system atrophy (MSA) over one year. Background: Identifying disease progression biomarkers is crucial for advancing MSA…Consideration of age and initial putaminal rim segment in distinguishing multiple system atrophy parkinsonian type
Objective: To improve diagnostic performance in distinguishing multiple system atrophy parkinsonian type (MSA-p), we investigated the iron deposition pattern in the putaminal lateral margin of…Network Localisation of Multiple System Atrophy
Objective: To apply a novel neuroimaging method, Coordinate-based Network Mapping (CNM)1, to localise heterogeneous neuroimaging findings in multiple system atrophy (MSA) into a functionally connected…An automated AI-based framework for putamen volume measurement in MSA
Objective: The putamen is a difficult structure to segment accurately, and automated methods require manual editing to improve segmentation accuracy. Our aim was to test…Deep gray matter atrophy in MSA subtypes
Objective: To compare MRI parameters of atrophy in Multiple system atrophy (MSA) subtypes. Background: MSA is a rare adult-onset synucleinopathology that can be divided in…An Unusual Case of Multiple Systems Atrophy with Long Disease Duration, Severe Gliosis, and Scant Synuclein Pathology
Objective: To describe a pathologically unusual case of Multiple systems atrophy (MSA) with severe widespread gliosis and neuronal loss with scant alpha-synuclein (aSyn) pathology. Background:…Automated Midbrain-Pons Ratio using Artificial Intelligence Differentiates PSP from other Atypical Parkinsonian Disorders
Objective: Our primary goal was to implement an automated measure of the midbrain to pons ratio (MPR) using an artificial intelligence method. Our second objective…Abnormal pattern of brain glucose metabolism in multiple system atrophy
Objective: To define and cross-validate the brain glucose metabolic abnormalities in patients with a clinical diagnosis of Multiple System Atrophy (MSA). Background: Despite the availability…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.