The Roche ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development – Focus on Parkinson’s disease
Objective: To develop an ‘End-to-End Matrix’ for Patient-Centric Drug Discovery and Development to increase the probability of success of clinical trials in Parkinson’s disease. Background:…Empowerment of People with Parkinson`s disease: development, testing and evaluation of a cross-sectoral, intervention-based self-management program
Objective: The overall purpose of this study is to develop, test and evaluate the results of a self-management program targeted PwP with the aim of…Tongue fasciculations and numbness: A case of calcifying pseudoneoplasm
Objective: To describe a 61-year-old female who presents with abnormal tongue movement found to have right frontoparietal calcifying pseudoneoplasm of the neuraxis (CAPNON). Background: CAPNON…Safety in Levodopa/carbidopa Intestinal Gel (LCGI) titration in the Intensive Care Unit (ICU) setting for Parkinson’s Disease (PD) patient with severe dysphagia
Objective: Describe a PD patient with obsessive-compulsive disorder (OCD) and paranoid symptoms in whom treatment with LCIG was started in the ICU due to severe…Transforming Parkinson’s Care in Africa: community engagement and involvement activities
Objective: To outline the role of community engagement and involvement (CEI) in global health research to support people with Parkinson’s and their caregivers across Africa.…A novel model of care for an integrated movement assessment program (I-MAP) targeted for patients with movement disorders
Objective: To provide an integrated hub where assessment and recommendations on medical, physical, functional, psychosocial needs are made efficiently, and care co-ordination and support services…Integrating care coordination into telemedicine services provides a better patient experience than care coordination alone: Insights from a national neurodegenerative disease telemedicine program
Objective: To develop a comprehensive model of remote care for patients diagnosed with Parkinson’s disease (PD). Background: Recent data suggests that the incidence of new…Taking the driver’s seat on Parkinson’s care
Objective: To provide insight into the unique service and support offered by the multidisciplinary health team to address the challenges and dilemmas faced by people…Targeted sequencing of regulatory regions shows potential SNVs affecting FXN gene expression in Friedreich’s ataxia patients
Objective: To investigate variations in regulatory regions of the FXN gene hampering its expression in Friedreich’s Ataxia (FRDA) patients. To investigate variations in regulatory regions…A baseline study for the first year of a diverse Parkinson’s Disease interdisciplinary clinic
Objective: To characterize patients at a new diverse, academic Parkinson’s Disease (PD) interdisciplinary clinic (IDC). Background: PD affects patients in nearly all spheres of life,…
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