Parkinsonism alters directed connectivity in the cortico-subthalamo-pallidal circuit
Objective: To characterize how parkinsonism alters directed connectivity across the motor cortex (M1), subthalamic nucleus (STN), and internal segment of the globus pallidus (GPi). Background:…Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Objective: Using opto-activation of cortical interneurons, we aimed at mimicking the cortical effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) to reproduce its…Ponto-cortical aberrations:Neural correlations for Hypomimia in PD
Objective: We team neuron, focused on analyzing progressive degeneration of neural structural connectivity of the tract from Brodmann area 4, part precentral gyrus to facial motor…Motor cortical inhibitory and facilitatory circuit interactions in Parkinson’s disease
Objective: To determine how intracortical circuits interact with one another in Parkinson’s disease. Background: Using transcranial magnetic stimulation (TMS), previous work has established that motor…Beta burst coupling across the motor circuit in patients with Parkinson’s disease
Objective: Here, we test the hypothesis that beta bursts not only involve dynamically elevated local synchronisation but also distributed coupling across circuit nodes, further restricting…Gender Differences in Parkinson’s disease: Transcranial Magnetics Stimulation Study of Newly Diagnosed Drug-Naïve PD Patients
Objective: In early Parkinson’s disease (PD), functional changes may be detected in primary motor cortex (M1) using transcranial magnetic stimulation (TMS). We hypothesised that, if…Apathy in Parkinson’s disease is associated with abnormal alpha oscillatory behaviour during incentivized movement
Objective: To determine the relation between apathy and neural oscillations in Parkinson’s disease (PD). Background: Apathy in PD, characterized by lack of motivation, is often…Neurophysiological correlates of bradykinesia in Parkinson’s disease
Objective: In the present study we aimed to investigate whether objective measures of bradykinesia in Parkinson’s disease have any relationship with neurophysiological measures in primary…The Ultrastructural study of the effects of different types of chronic motor deficit on the morphology of limbic, extrapyramidal and neocortical regions of rat brain
Objective: To study the effect of chronic restraint stress and moderate motor deficit on the ultrastructure of central and lateral amygdalar nuclei, hippocampal CA1 and…Dual Competition between the Basal Ganglia and the Cortex: 1 from Action-Outcome to Stimulus-Response
Objective: We propose a model of the interaction between the cortex, the basal ganglia and the thalamus based on a dual competition during instrumental conditioning.…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.