Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Objective: Using opto-activation of cortical interneurons, we aimed at mimicking the cortical effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) to reproduce its…Ponto-cortical aberrations:Neural correlations for Hypomimia in PD
Objective: We team neuron, focused on analyzing progressive degeneration of neural structural connectivity of the tract from Brodmann area 4, part precentral gyrus to facial motor…Case Report: Co-occurrence of Motor Neuron Disease and Parkinsonism
Objective: Explore possible links between degenerative parkinsonism and motor neuron disease Background: A 50 year-old man developed with the cardinal features of parkinsonism. History was…Effects of the Neuromodulation of Sensorimotor Rhythms on the Event-Related Desynchronization Phenomenon in Parkinson’s Disease
Objective: The main goal of this work relies on the study of the desynchronization of the sensorimotor rhythms in Parkinson’s disease (PD). Electrophysiological cortical activity…Motor intracortical excitability before speech onset in adults who stutter
Objective: A core feature of persistent developmental stuttering is the paroxysmal, transient, involuntary loss of speech motor control. However, the neurophysiology of stuttering remains largely…Impaired intracortical inhibition predicts response to medication in Parkinson’s disease patients
Objective: To check whether measures of motor cortex excitability and plasticity are associated with clinical response to dopaminergic treatment in Parkinson’s disease (PD) patients. Background:…Impaired LTP-like plasticity in Parkinson’s Disease can be restored by γ-transcranial alternating current stimulation
Objective: To test whether the co-stimulation γ-transcranial alternating current stimulation (γ-tACS)-intermittent theta burst stimulation (iTBS) is effective in improving the impaired long-term potentiation (LTP)-like plasticity…Cortical gamma oscillations as biomarkers for levodopa-induced dyskinesia
Objective: The aim of our study was to characterize cortical neuronal network activity in levodopa-induced dyskinesia in order to better understand the underlying pathophysiology and…To respond or not to respond to paired associative stimulation: proof of intervention by cerebello-cortical circuit
Objective: To test whether the non-responder or responder status of primary motor cortex (M1) to an LTP- inducing paired associative stimulation (PAS) protocol in healthy…Early synaptic loss and synaptic instability in a mouse model of prodromal Parkinson’s disease
Objective: In order to elucidate very early pathologis of Parkinson’s disease (PD), we focused on synaptic pathologies in a newly developed mouse model of prodromal…
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