Parkinsonism alters directed connectivity in the cortico-subthalamo-pallidal circuit
Objective: To characterize how parkinsonism alters directed connectivity across the motor cortex (M1), subthalamic nucleus (STN), and internal segment of the globus pallidus (GPi). Background:…Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Objective: Using opto-activation of cortical interneurons, we aimed at mimicking the cortical effects of deep brain stimulation of the subthalamic nucleus (STN-DBS) to reproduce its…Ponto-cortical aberrations:Neural correlations for Hypomimia in PD
Objective: We team neuron, focused on analyzing progressive degeneration of neural structural connectivity of the tract from Brodmann area 4, part precentral gyrus to facial motor…Neurophysiological correlates of bradykinesia in Parkinson’s disease
Objective: In the present study we aimed to investigate whether objective measures of bradykinesia in Parkinson’s disease have any relationship with neurophysiological measures in primary…The Ultrastructural study of the effects of different types of chronic motor deficit on the morphology of limbic, extrapyramidal and neocortical regions of rat brain
Objective: To study the effect of chronic restraint stress and moderate motor deficit on the ultrastructure of central and lateral amygdalar nuclei, hippocampal CA1 and…Dual Competition between the Basal Ganglia and the Cortex: 1 from Action-Outcome to Stimulus-Response
Objective: We propose a model of the interaction between the cortex, the basal ganglia and the thalamus based on a dual competition during instrumental conditioning.…Effects of rTMS on three cortical areas in Parkinson’s Disease
Objective: To evaluate the role of rTMS over primary motor area, premotor area, supplementary motor area in Parkinsons Disease. Background: Parkinson’s disease (PD) presents with…Early synaptic loss and synaptic instability in a mouse model of prodromal Parkinson’s disease
Objective: In order to elucidate very early pathologis of Parkinson’s disease (PD), we focused on synaptic pathologies in a newly developed mouse model of prodromal…Further insights into excitatory-inhibitory balance of the primary motor cortex in Parkinson’s disease: A triple-pulse stimulation study
Objective: To characterize intracortical facilitation and inhibition of the primary motor cortex (M1) in Parkinson’s disease (PD) using transcranial magnetic stimulation (TMS). Background: Since introduction…Neuromodulation by rTMS in Parkinsons Disease: A fMRI Study
Objective: To compare the efficacy of rTMS [when given at primary motor area (MA), pre-motor area (PMA), supplementary motor area (SMA)] in Patients with Parkinson’s…