Continuous wavelet transforms to improve the accuracy of motor assessments of Parkinson’s disease
Objective: We sought to develop a protocol to utilize continuous wavelet transforms (CWTs) to rate the severity of movements to obtain optimal classifications of PD.…Patient-specific multivariate gray matter volumetric distance to predict disease severity in Parkinson’s disease
Objective: Identifying novel biomarkers to predict disease progression is of paramount importance in patients with Parkinson’s disease (PD). In this study, we utilized Structural Magnetic…P2B001 in the management of untreated PD. Results from a randomized, double-blind, double-dummy controlled trial
Objective: Evaluate the efficacy and safety of P2B001 compared with its components and with Extended-Release pramipexole (ER-PPX, calibration arm) in untreated PD. Background: P2B001 is…Evaluation of an Oral Health Questionnaire in Parkinson’s Disease to Facilitate a Multi-disciplinary Approach to improving Care Through Education
Objective: To determine if the oral health questionnaire (OHQ) devised could help to promote good oral hygiene in Parkinson’s disease (PD) while considering the potential…Impaired Imagery of Tremor in Patients with Essential Tremor
Objective: To investigate neural mechanisms underlying motor imagination (MI) in essential tremor (ET) patients compared to healthy controls using high-density EEG. Background: ET ranges among…The impact of thyroid disease on severity of motor symptoms in Croatian residents with de novo Parkinson’s disease
Objective: The goal of this study was to investigate the association between thyroid disease and severity of motor symptoms in Croatian residents with de novo…Motor decision-making in Parkinson’s disease
Objective: The aim of this study is to test motor decision-making ability in Parkinson's disease (PD) in conditions with different biomechanical properties and levels of…Detecting Parkinson’s Disease from body limb acceleration using machine learning and a frequency-domain analysis
Objective: To test whether the acceleration frequency of different body parts during gait can reveal characteristic patterns of Parkinson’s Disease (PD). The technical aim was…Effect of KW-6356, a novel adenosine A2A receptor antagonist/inverse agonist, on motor and non-motor symptoms in Parkinson’s disease patients as an adjunct to levodopa therapy: Results of Phase 2b study
Objective: To evaluate the efficacy and safety of KW-6356 in Parkinson’s disease (PD) patients with levodopa therapy, irrespective of the presence of wearing-off (WO). Background:…Dopaminergic modulation of express reaching responses in Parkinson’s disease
Objective: This study investigates the role of dopamine (DA) in modulation of automatic stimulus-driven responses. We investigated the effect of PD, DA medication, and instruction…
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