Observations and Strategies for Improving Recruitment and Retention of Underrepresented Populations in Movement Disorders Clinical Research Trials Conducted in a Tertiary Research Site
Objective: To observe the improvement in one tertiary clinical site of the recruitment of underrepresented populations with a focus on the Asian demographic and note…Sustained Motor Symptom Efficacy With Long-Term Levodopa–Entacapone–Carbidopa Intestinal Gel (LECIG) Treatment – Data From The ELEGANCE Interim Analysis
Objective: To evaluate the long-term effect on motor symptoms of advanced Parkinson’s disease (PD) following up to two years of treatment with LECIG by analysis…Decoding Naturalistic Movement for Adaptive Deep Brain Stimulation in Parkinson’s Disease
Objective: To demonstrate the proof-of-concept of a closed-loop deep brain stimulation (DBS) policy designed to reduce slowness in Parkinson’s disease (PD) by increasing stimulation amplitudes…Neuroprotective Effects of Co-Administered Hesperetin and Resveratrol Nanoparticles on Oxidative Stress and Neurobehavioral Deficits in Parkinson’s Disease
Objective: This study aimed to evaluate the therapeutic potential of solid lipid nanoparticles (SLNs) containing hesperetin (HE-SLN), resveratrol (RE-SLN), and their co-administration (HE-RE-SLN) in combating…Therapeutic Potential of GLP-1 Receptor Agonists in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: To assess the safety and effectiveness of GLP-1 RAs in patients with PD. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by…Perinatal Dioxin Exposure and Dopaminergic Vulnerability in the Development of Motor Dysfunction Sequelae
Objective: To investigate the impact of dioxins on movement disorder development and the mechanisms increasing vulnerability to future motor dysfunction. Background: Dioxins are persistent organic…Single- and Multi-Unit Activity in STN Provides Enhanced Insight into Speech-Related Neural Dynamics in Parkinson’s Patients
Objective: We aimed to elucidate neural representations in local field potentials (LFP) and single- and multi-unit activity of subthalamic nucleus (STN) neurons during speech tasks,…Boosting Education and Awareness Together for people with Parkinson’s Disease (BEATs-PD): Methodological Considerations in Research Co-Creation
Objective: To describe methodological considerations related to stakeholder engagement in community-based participatory research (CBPR) to create a dance and music-based program (DMBP) for people with…Daily Activity Analysis of Parkinson’s Disease Using Machine Learning with 3D Poses
Objective: This study aims to find a digital behavioral marker Parkinson’s disease (PD) in activities of daily living via machine learning (ML) analysis of 3D…Dose Optimization of Foslevodopa/Foscarbidopa: Post Hoc Analysis of Study Completers
Objective: To describe dose optimization, efficacy, and safety of foslevodopa/foscarbidopa (LDp/CDp) in patients with advanced Parkinson’s disease (PwaPD) who completed a 52-week open-label study. Background:…
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