The effect of levodopa-carbidopa intestinal gel on activities of daily living: Results from the observational MONOTREAT study in advanced Parkinson’s disease patients
Objective: To assess the tolerability and effect of levodopa-carbidopa intestinal gel (LCIG, designated in the United States as carbidopa-levodopa enteral suspension) on activities of daily…Parkinson’s disease is characterised by differences in lower limb joint kinetics during stair ascent and descent
Objective: To investigate the contribution of the hip, knee and ankle joint moments to support moments during stair ascent and descent in people with Parkinson's…Parkinson’s disease onset on non-dominant side predicts greater motor disability
Objective: Evaluate (1) the effect of dominant-side onset (DSO) vs non-dominant-side onset (NDSO) of Parkinson's disease (PD) on motor impairment in a large multicenter cohort…The feasibility of measuring fatigability in early-stage Parkinson’s disease using functional MRI
Objective: To investigate the effect of fatiguability on brain activation in people with Parkinson's (PwP) in comparison with healthy volunteers(HV). Background: Fatiguability, an objective decline…Improving clinical detection of balance deficits in individuals with Parkinson’s disease with and without freezing of gait and the effects of dopaminergic replacement therapy
Objective: Since it has been argued that PD+FOG have greater sensory impairments compared to PD-FOG, the current study evaluated whether the modified Clinical Test of…The role of acoustic salience in acoustic cueing and sound-based motor rehabilitation
Objective: To evaluate the underlying mechanisms for motor rehabilitation in acoustic cueing and sound therapies with a specific focus on patterns of auditory salience. Background:…Differential clinical outcomes in unifocal vs. multifocal premotor rTMS for Parkinson’s disease: A randomized trial
Objective: To compare changes in clinical outcomes after weekly low-frequency (LF) repetitive transcranial magnetic stimulation (rTMS) sessions over one vs. two pre-motor cortex (preMC) areas…Statistical aspects when exploring the association between change in body mass index (BMI), UPDRS scores and survival in the NET PD long-term study-1
Objective: To report the statistical analyses exploring the association between BMI and change in Unified Parkinson's disease Rating Scale (UPDRS) scores and survival in the…Age associated effects of levodopa administration on striatal acetylcholinesterase activity
Objective: The aim of this study was to compare short- and long-term effects of levodopa on acetylcholinesterase activity in young and old rat brain striatum.…Alterations in muscle synergies in early stage Parkinson’s disease
Objective: Identify whether muscle synergies are altered in stage I Parkinson's disease (PD). Background: Muscle synergies have been proposed as a mechanism utilized by the…