Utility of a smartphone app in discretely assessing and monitoring symptoms of Parkinson’s disease
Objective: To assess the utility of a cognitive and motor battery on a smartphone/smart watch combination in an at-home setting for remote assessment of PD…Long-Term Treatment With Deutetrabenazine Is Associated With Continued Improvement in Tardive Dyskinesia: Results From an Open-Label Extension Study
Objective: To evaluate long-term efficacy of deutetrabenazine in patients with tardive dyskinesia (TD) by examining the change from baseline in Abnormal Involuntary Movement Scale (AIMS)…Swimming in PD patients with STN-DBS: A pilot exploratory study
Objective: Patients with PD frequently complain of losing abilitiy to swim. Our aim was to test the swimming abilities of our patients with bilateral STN-DBS…Does the Parkinson’s Kinetigraph change clinical practice?
Objective: To assess whether information obtained from Parkinson’s Kinetigraph (PKG) influences clinical decision-making. Background: PKG is a relatively new technology: the device is worn continuously…Motivational effects on action selection and memory
Objective: Eye movements provide important insights into the pathophysiology of neurological disorders. Here two paradigms were devised to quantify effects of motivation on motor control…Dissociative effects of thyrotropin releasing hormone on classical cerebellar ataxic signs and cerebellar adaptation in patients with spinocerebellar degeneration
Objective: To reveal effects of TRH [Thyrotropin releasing hormone (protirelin tartrate)] on the prism adaptation task in patients with spinocerebellar degeneration (SCD). Background: The cerebellum…Pilot economic evaluation of Personal KinetiGraph (PKG) for management of Parkinson’s disease in Australia
Objective: To determine the potential cost savings and quality of life gains with the Personal KinetiGraph (PKG) in the management of patients with Parkinson’s disease…Influence of dopamine deficiency on interhemispheric crosstalk in Parkinson’s disease
Objective: To identify the significance of dopaminergic depletion in Parkinson’s disease (PD) on interhemispheric crosstalk using a complex bimanual tapping task. Background: Dopamine deficiency in…A randomized, double-blind, placebo-controlled Phase II Efficacy and Safety Study of the PDE10A inhibitor PF-02545920 in Huntington Disease (AMARYLLIS)
Objective: To assess efficacy on motor function, safety and tolerability of the phosphodiesterase-10A inhibitor PF-02545920 in Huntington disease (HD). Conclusion: PF-02545920 was generally safe and…Costs and outcomes for Parkinson’s disease patients who have their management adjusted by Personal KinetiGraph (PKG)
Objective: To quantify the potential cost savings and quality adjusted life years (QALYs) gained for people with Parkinson’s disease in Australia whose oral therapy was…
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