What connectivity tells us about neurodegeneration in Huntington disease? A fMRI study
Objective: Our study investigated the impact of Huntington disease (HD) on brain connectivity, through resting-state (RS) fMRI, among the most critical regions associated with physiopathology.…A general impaired-rhythm system underpins oro-motor, manual, and gait rhythmic disturbances in Parkinson’s disease
Objective: To assess whether rhythmic disturbances in three different domains (i.e., oro-motor, finger tapping and gait domains) are related in Parkinson's disease (PD), and to…Gender differences for Motor and non motor symptoms in Parkinson’s Disease among Pakistani population
Objective: Parkinson’s disease is second most common neurodegenerative t disorder with increasing burden in under developed countries with poor health facilities. Motor and non motor…The Effect of Gocovri on Motor Aspects of Experiences of Daily Living: Analyses of MDS-UPDRS Part II Data from a Phase 3 Program
Objective: To assess the impact of Gocovri® (amantadine) extended release capsules on motor aspects of experiences of daily living in PD patients. Background: Gocovri is…Evaluation of Constipation in Patients with Parkinson’s Disease and its Correction
Objective: To evaluate the possible causes of constipation, and to find clear methods to correct the disorder. Background: Constipation is a common problem in Parkinson's…One-year follow-up of subthalamic deep brain stimulation in Parkinson’s disease
Objective: To report the results of one-year follow-up of subthalamic deep brain stimulation in Parkinson's disease on 19 patients bilaterally implanted at Federal University of…Use digital sensor and deep learning to evaluate motor performance in the D1PAM (LY3154207) phase 1B Parkinson’s disease clinical trial
Objective: This study aims to test the feasibility of using digital tools to evaluate motor performance in a Parkinson’s disease clinical trial. Background: Modern smartphones…Objective assessment of motor states in Parkinson’s disease using partial least squares and smartphone data
Objective: In this study, we will investigate the behaviour of Partial Least Squares (PLS) regression for dimension reduction and prediction of motor states of Parkinson’s…Intraoperative test stimulation of the subthalamic nucleus reduces the search space for chronic stimulation settings in Parkinson’s disease
Objective: To determine whether intraoperative test stimulation is indicative of postoperative stimulation results. Background: It is unknown whether intraoperative testing during awake Deep Brain Stimulation…Opicapone added to safinamide in patients affected by Parkinson’s disease for better controlling motor fluctuations
Objective: The aim of this clinical observation was to verify the sparing of levodopa in patients affected by Parkinson's disease who already started safinamide treatment for…
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