Dopamine substitution increases connectivity between premotor and motor areas in Parkinson’s disease – a DCM-Study
Objective: To assess the influence of dopaminergic depletion in Parkinson’s disease (PD) on connectivity parameters within the cortical motor network. Background: Integration of neuronal information…Speech impairment as a marker of clinical changes in premanifest Huntington’s disease
Objective: Speech disturbances have been described in premanifest Huntington’s Disease (HD). Yet a recent systematic review and meta-analysis highlighted disagreement in the literature regarding the…Healthcare disparities in patients with Parkinson’s disease: A comprehensive literature review and call to action
Objective: To review the literature on healthcare disparities in Parkinson’s care in the United States and to initiate a community education program targeted at an…Advanced Stage of Parkinson’s Disease: From Identification to Characterization and Disease Burden Assessment Using a Nationwide Database
Objective: To identify and describe PD patients who were prescribed intensified therapy and compare their burden of disease with mild-moderate PD patients. Background: Real-world data…Neuronal correlates of oculomotor alterations in Huntington’s disease. A 18-FDG PET study
Objective: To explore the neuroanatomical correlates of the oculomotor abnormalities in Huntington's disease (HD) through a 18-FDG PET study Background: Alterations of the oculomotor function…Safety and efficacy of high definition tDCS for proprioception and balance in Parkinson’s disease: A pilot randomised trial
Objective: To determine: 1. Is HD-tDCS safe and well-tolerated in PD? 2. Does combined HD-tDCS and physical exercise improve proprioception and balance in PD? Background:…Ankle proprioception and postural instability in Parkinson’s disease
Objective: To determine: 1. Is there a correlation between central and peripheral proprioception in Parkinson’s disease? 2. Does postural instability increase with lack of vision…Evaluation of motor impulsivity in Huntington Disease with a choice reaction time task and brain metabolic (PET 18FDG) imaging
Objective: To describe motor impulsivity in early Huntington disease (HD) with electromyographic (EMG) recordings during a choice reaction time task (Simon Task) and brain metabolic…The impact of a wearable device on Parkinson’s disease motor symptom management in patients starting rotigotine transdermal patch
Objective: Open-label, multi-center pilot study (PD0049) to evaluate the impact of Kinesia 360 (an “at home” wearable device) on motor symptom management in Parkinson’s disease…Safinamide in Parkinson’s disease
Objective: To evaluate clinical effects, safety and tolerability of safinamide add-on levodopa in Parkinson’s disease (PD) patients. Background: Safinamide is a recently approved adjunctive treatment…
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