Bayesian Estimation of Gait Cadence from Monocular Video
Objective: Walking (gait) is a crucial motor function, and is frequently assessed as a component of clinical examination and subsequent patient management. However, the assessment…Probing the Parieto-Premotor Network in Writer’s Cramp Using Transcranial Magnetic Stimulation
Objective: We aimed to probe the parieto-premotor network using transcranial magnetic stimulation (TMS), and further investigate its influence on the motor cortex in patients with…Kinematic assessment of bradykinesia in patients with amyotrophic lateral sclerosis
Objective: To kinematically assess abnormalities of voluntary upper limbs movements in patients with amyotrophic lateral sclerosis compared to healthy subjects. To investigate possible relationships between…Hand Fine Motor Performance Capacity is Associated with the Cognition in People with Moderate to Advanced Parkinson’s disease
Objective: This study aims to investigate the association between the hand fine motor performance with the cognitive dysfunction in people with moderate and severe PD.…Deficient Balance Mechanisms during Walking in People with Parkinson’s Disease
Objective: Investigate whether people with Parkinson’s disease (PD) have deficient balance mechanisms following visual perturbations during walking. Background: We recently showed that maintaining upright balance…Rhythmic activity of subthalamic neurons during externally and internally generated movements in Parkinson’s disease
Objective: To find the specificity of neuronal responses in the subthalamic nucleus during externally and internally generated voluntary movements in Parkinson’s disease. Background: The motor…Rhythmic movements decompose in Parkinson’s disease with worse disease severity at low frequencies: akinesia or impaired ability to move more slowly than comfortable?
Objective: To explore the relationship between disease severity, minimum comfortable velocity and dwell time in Parkinson's disease. Background: People find it hard to move smoothly…Motor onset of Parkinsonʼs disease: Is there a somatotopic pattern?
Objective: To study the clinical onset and progression of motor manifestations in different body regions in early PD patients. Background: The vulnerability of the nigrostriatal…Real Time Quality Control for Subjective Endpoints in Clinical Trials
Objective: Here we present a system which is capable of performing nearly-real time monitoring of UPDRS part-3 motor assessments using a combination of multidimensional statistics…A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AKST4290 in Subjects with Parkinson’s Disease on Stable Dopaminergic Treatment (TEAL Study)
Objective: Assessment of efficacy and safety in subjects with Parkinson’s disease (PD) following treatment for 12 weeks with placebo or AKST4290, a highly specific and…
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