Grey matter atrophy associated with the progression of cognitive decline in Parkinson’s disease (PD)
Objective: To investigate the pattern of grey matter (GM) atrophy associated with cognitive decline in PD by use of voxel-based morphometry (VBM) analysis. Background: Loss…Accuracy of intraoperative CT during DBS procedures: Comparison with postoperative MRI
Objective: To determine the accuracy of intraoperative CT (iCT) in localizing deep brain stimulation (DBS) electrodes by comparing this modality with postoperative magnetic resonance imaging…Reduced thalamo-cortical functional connectivity in asymptomatic LRRK2 mutation carriers
Objective: To characterize MRI functional patterns during resting state in asymptomatic LRRK2 mutation carriers. Background: Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are…Early grey matter changes in structural covariance networks in Huntington’s disease
Objective: To identify network integrity changes in Huntington's disease (HD) using grey matter whole brain structural covariance networks and to examine relationships between anatomical networks…Resting state functional connectivity in olfactory network in de novo Parkinson’s disease
Objective: To assess the pattern of RS functional connectivity in PD patients, related to olfactory psychometric test, to elucidate olfactory-dependent cortical-subcortical functional networks. Background: Olfactory…Increased cortical control of gait in patients with Parkinson’s disease and freezing of gait
Objective: To determine structural connectivity between the mesencephalic locomotor region (MLR) and the supplementary motor area (SMA) in freezers compared to non-freezers. Background: Freezing of…Reward insensitivity differentiates apathy from depression in Parkinson’s disease
Objective: To determine if a potential cause of apathy in Parkinson's disease (PD) might be insensitivity to rewards, establish if this differentiates apathy from depression…Comparison of clinically derived and model based programming parameters of subthalamic nucleus stimulation in Parkinson’s disease
Objective: To test whether DBS parameters in chronically stimulated Parkinson´s disease (PD) patients chosen by clinical criteria are congruent with DBS parameters as derived from…Integrity of the superior longitudinal fascicle and its relationship with anticipatory postural adjustments in people with Parkinson’s disease and freezing of gait
Objective: To assess the integrity of the Superior Longitudinal Fascicle (SLF) and its relationship with the Anticipatory Postural Adjustments (APAs) of step initiation in people…Structural connectivity networks in prodromal and clinical Huntington’s disease
Objective: To investigate how structural connectivity correlates with the number of CAG repeats, disease evolution and clinical measures in presymptomatic (preHD) and clinical Huntington Disease…
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