The value of multi-slice computed tomography angiography in diagnosis of intracranial circulation in patients with vascular parkinsonism
Objective: The purpose of research was to evaluate the results of multislice computed tomographic angiography (MSCTA) in patients with vascular parkinsonism (VP) with stenotic lesions…Neuroanatomical correlates of apathy in non-demented and non-depressed Parkinson’s disease
Objective: We aimed to explore the neuroanatomical correlates of isolated apathy in PD by means of voxel-based morphometry (VBM) analysis and its correlates with other…Ultra high field magnetic resonance imaging of nigrosome 1 is a biomarker of new onset and premotor Parkinson’s disease
Objective: An unmet need exists to develop a methodology to diagnose Parkinson's disease (PD) in the premotor stage, so that patients can be enrolled in…In-vivo free-water imaging and functional connectivity in a knock-in mouse model of DYT1 dystonia
Objective: To examine in-vivo functional connectivity and free-water diffusion imaging in dystonic mutant Tor1a knock-in (DYT1) and wild-type (WT) control mice. We test the hypothesis…Manual MRI morphometry in Parkinsonian syndromes
Objective: We investigated a large sample of Parkinsonian patients and healthy controls from five German academic medical centers with 3D MP-RAGE sequences on mainly 3T…Is levodopa-induced dyskinesia in Parkinson’s disease associated with increased blood brain barrier permeability and volumetric changes?
Objective: The aim of this study was to explore the angiogenetic hypothesis for Levodopa-induced-dyskinesia (LID) using advanced MRI methods in patients with Parkinson's disease (PD).…Cerebellar GABA in essential tremor and dystonic tremor: A MR spectroscopy study
Objective: To explore the role of GABA in the pathophysiology of ET and DT by using MR spectroscopy. Background: The mechanisms of tremor in ET…Progressive atrophy of parahippocampal gyrus correlates with Hoehn & Yahr stages of Parkinson’s disease: A voxel based morphometric study
Objective: To determine the gray matter (GM) changes in different clinical stages of Parkinson's disease (PD) using Voxel Based Morphometry (VBM). Background: PD is a…Detecting brainstem changes in Parkinson’s disease using quantitative MRI
Objective: 1. Can brainstem changes be detected using quantitative MRI (qMRI). 2. How many subjects would be required to detecting changes in brainstem regions affected…Striatal postsynaptic dysfunction in X-linked dystonia-parkinsonism is associated with disease progression
Objective: To assess pre- and postsynaptic dopaminergic function in X-linked dystonia-parkinsonism (XDP). Background: X-linked dystonia-parkinsonism (XDP) is a neurodegenerative adult-onset movement disorder associated with striatal…
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