Imaging Parkinson’s disease pathology: A comparison between neuromelanin-sensitive MRI, susceptibility weighted imaging and [11C]PE2I DAT PET
Objective: We compared 2 novel MRI techniques: neuromelanin-sensitive MRI (NM-MRI) and susceptibility weighted imaging (SWI) with [11C]PE2I PET in order to establish their validity as biomarkers…Braak model in Parkinson disease using MRI biomarkers
Objective: The aim of this study was to test using multimodal MRI biomarkers if the pattern of neurodegeneration in the brain of patients with PD…MCI reverters have a favorable cognitive prognosis and cortical integrity in Parkinson’s disease
Objective: To investigate whether reversion to cognitively normal status (CogN) is clinically relevant in Parkinson’s disease with mild cognitive impairment (PD-MCI). Background: The concept of…Structural connectome of brainstem nuclei in REM sleep behavior disorder, a model of premanifest synucleinopathy
Objective: To investigate in vivobrainstem structural connectivity changes in a model of premanifest synucleinopathy, REM sleep behavior disorder (RBD), using 7 T high spatial-resolution diffusion-tensor-imaging (DTI)…Longitudinal Analysis of the Corticospinal tract microstructure in Parkinson’s Disease Patients
Objective: To assess longitudinal abnormlities throughout the corticospinal tract in Parkinson’s Disease patients. Background: Parkinson’s Disease (PD) is a neurodegenerative progressive disease might become a pandemic…Structural imaging changes in hepatic and neurological Wilson disease
Objective: To quantitatively assess cerebral structural changes in Wilson disease (WD) subjects with hepatic and neurological phenotypes. Background: WD is a rare autosomal recessive disorder…Heterozygous DCC mutations, more than congenital mirror movements
Objective: To perform a comprehensive characterization of 5 patients with variable degree of congenital mirror movements. Background: Congenital mirror movements (CMM) are rare non-progressive syndromes…Neuromelamin-MRI in patients with Pure Autonomic Failure
Objective: To assess the utility of neuromelanin-MRI (NM-MRI) methods in a prodromal alpha-synuclein disorder, Pure Autonomic Failure (PAF). Background: PAF is a peripheral alpha-synucleinopathy (AS)…Semantic fluency impairment and amygdala atrophy are predictive factors for the development of Parkinson’s disease dementia
Objective: We investigated neuroanatomical differences between Parkinson’s disease (PD) patients with and without semantic fluency impairment and explored predictive markers for dementia development. Background: Sematic…The radiofrequency (RF)-induced heating profile of an externalized, directional DBS lead using functional imaging sequences in an Intraoperative Magnetic Resonance Imaging Suite (IMRIS)
Objective: To characterize the RF-induced heating profile of the St. Jude Infinity lead within an IMRIS using a configuration that emulates intraoperative functional MRI during…
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