Decoding Parkinson’s Progression: Longitudinal Volumetric MRI Biomarkers in Prodromal and Clinical Stages
Objective: This study investigates MRI volumetric analysis via VBM as a biomarker for early PD detection, focusing on structural alterations in deep gray matter regions…Linking Adolescent Brain Development To Parkinson’s Disease Risk Using Machine Learning On Polygenic Risk Scores
Objective: Examine whether adolescent brain structural deviations contribute to Parkinson’s disease (PD) susceptibility. Background: Genetic variants associated with PD have been linked to neurodevelopmental processes,…Differentiating White-Matter Damage Patterns by Underlying Pathology in Corticobasal Syndrome
Objective: This study aims to describe the patterns of white-matter damage using diffusion tensor imaging (DTI) in individuals with Corticobasal Syndrome (CBS) and compare the…A RNF213 truncating variant causes an autosomal dominant disorder with brainstem and basal ganglia lesions and a Huntington-like phenotype
Objective: To report a novel stop-gain variant in the RNF213 gene in two individuals, a father and son, presenting with variable neurologic presentations and similar…Prevalence and Clinical Characteristics of iNPH-Related Imaging Findings (DESH) in Parkinson’s Disease
Objective: To investigate the prevalence of idiopathic normal pressure hydrocephalus (iNPH)-related imaging findings (DESH) and their clinical characteristics in Parkinson’s disease (PD) patients. Background: PD…Minimally Invasive Magnetic Resonance Imaging guided Deep Brain Stimulation for Movement Disorders – A Novel technique, Accuracy and Clinical Outcome.
Objective: To study the accuracy of lead placement and clinical outcome of a novel technique using twist drill hole and smaller incision in Magnetic resonance…The Radiographic Overlap Between Normal Pressure Hydrocephalus (NPH) and Progressive Supranuclear Palsy (PSP): When Looks Can Be Deceiving
Objective: To demonstrate the overlap on radiographic metrics between NPH and PSP. Background: The neuroradiological hallmark of NPH is non-obstructive ventriculomegaly (Evans’ index (EI) >0.3).…Asymmetric periodic lower limb movements and malignant hypertension as an initial manifestation of atypical posterior reversible encephalopathy syndrome (PRES)
Objective: Our aim is to report a case of unusual manifestation of atypical posterior reversible encephalopathy syndrome (PRES), which showed periodic lower limb movements and…Identification of Distinctive Iron Deposition Pattern in Subcortical Nuclei of Parkinson’s Disease using Radiomics: A 7T Susceptibility-Weighted Imaging Study
Objective: To develop the optimal radiomics signature of distinctive subcortical nuclei iron deposition pattern for diagnosis and differential diagnosis of Parkinson’s disease (PD) at 7T susceptibility-weighted imaging (SWI).…Genotype and age at onset drive vermis atrophy in CACNA1A and GAA-FGF14 related ataxias
Objective: To assess cerebellar volumetry using a deep learning method in patients with non-polyglutamine CACNA1A- or GAA-FGF14-related disease. Background: Ion channel dysfunction is a recurring…
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