Spatiotemporal Changes in Substantia Nigra Neuromelanin Content from Prodromal to Clinical Parkinson’s Disease
Objective: To investigate the voxel-wise spatiotemporal changes in neuromelanin-sensitive MRI (NM-MRI) signal in the substantia nigra and their relation to clinical scores of disease severity…White matter microstructural abnormalities in tremor dominant and non-tremor dominant Parkinson’s disease
Objective: To explore differences in white matter microstructural integrity in tremor dominant and non-tremor dominant Parkinson’s disease (PD) using tract based spatial statistics (TBSS). Background:…Normative vs. patient-specific brain connectivity in Deep Brain Stimulation
Objective: The objective of this study was to compare similarities and differences between patient-specific, disease-matched and normative structural connectivity seeding from deep brain stimulation (DBS)…Striatal neurodegeneration in the presymptomatic phase of X-linked Dystonia-Parkinsonism
Objective: To identify structural brain changes in patients with X-linked dystonia-parkinsonism (XDP) and non-manifesting carriers of the TAF1 SVA retrotransposon insertion (NMC). Background: XDP is…Free Water in Corpus Callosum is Sensitive to Parkinson’s Disease-related Cognitive Decline
Objective: The objective of this study was to determine if the novel diffusion metric, free water (FW), from two-tensor modeling could sensitively identify microstructural alterations…Thalamic nuclei volumes and intrinsic thalamic network in motor subtype in Parkinson’s disease
Objective: The aim of this study is to investigate the alterations of thalamic nuclei volumes and intrinsic thalamic network in patients with de-novo PD according…In vivo markers of anxiety in drug-naïve Parkinson’s disease
Objective: To investigate imaging and CSF markers of disease pathology associated with anxiety in drug-naïve idiopathic Parkinson’s disease (PD) patients. Background: Anxiety is a frequent…Diagnostic accuracy of MR planimetry in clinically unclassifiable parkinsonism
Objective: To determine diagnostic accuracy of P/M, MRPI, and new indices termed P/M2.0 and MRPI2.0 (multiplying P/M and MRPI by third ventricle width/frontal horns width…Quantitative susceptibility mapping images for the parcellation of the Subthalamic Nucleus: a possible role for targeting Deep Brain Stimulation
Objective: To investigate the iron distribution in STN in PD patients using QSM images. Background: Subthalamic Deep Brain Stimulation (DBS) is considered an effective treatment…Leveraging patient-specific models to optimize DBS monopolar review
Objective: The objective of this study was to determine if patient-specific anatomical imaging can be leveraged to optimize monopolar review. Background: Parkinson’s disease (PD) is…
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