Parkinson Disease with, but not without, Cognitive Decline Reveals Advanced Brain Aging
Objective: To investigate “brain age” in Parkinson disease (PD) with and without cognitive decline, and its correlation with motor and cognitive performance. Background: Although brain…Normal-sized Perivascular Space in Basal Ganglia Related to Motor Phenotypes in Parkinson Freezers
Objective: With 7T MRI, we aimed to study the relationship between the initial motor phenotype of Parkinson’s disease (PD) and normal-sized PVSs (nPVSs) burden in…Impaired ocular tracking in idiopathic REM sleep behavior disorder is associated with gray matter alterations
Objective: Using an established 15-min ocular-tracking task and structural MRI scanning, we examined the ocular tracking ability in iRBD patients and its anatomical correlates. Background:…Feasibility study of diffusion tensor imaging fiber tracking in PD patients after DBS operation
Objective: To explore the feasible of depicting the nigrostriatal pathway (NSP), dentate rubro thalamic (DRTT) and hyperdirect pathway (HDP) for the postoperative PD patients with…Locus coeruleus degeneration associated with less levodopa responsiveness in Parkinson’s Disease
Objective: We aimed to explore the relationship between LC degeneration and levodopa responsiveness in Parkinson’s Disease (PD) patients in vivo. Background: Widely divergent responsiveness of…Sex-Specific White Matter Correlates of Neuropsychological Measures in Parkinson’s disease with Mild Cognitive Impairment
Objective: To identify sex-specific white-matter (WM) correlates of neuropsychological measures in Parkinson’s disease (PD) with mild cognitive impairment (MCI). Background: Neuropsychological measures of executive function…Does neurodegeneration of the noradrenergic locus coeruleus follow a spatial gradient in Parkinson’s disease?
Objective: To map degeneration of the locus coeruleus in Parkinson’s disease in-vivo using ultra-high field MRI. Background: Parkinson’s disease (PD) causes degeneration of dopaminergic neurons…Increased free-water in the substantia nigra in idiopathic REM sleep behaviour disorder
Objective: In this study, we tested the hypothesis that free water is elevated in the posterior substantia nigra of idiopathic rapid eye movement sleep behaviour…White matter and cognition in Parkinson’s disease
Objective: Examine whether a recently developed MRI biomarker intended to assess cerebrovascular small vessel disease, peak width of skeletonized mean diffusivity (PSMD)[1], predicts cognitive decline…Sex differences in brain and cognition in de novo PD patients
Objective: We aimed to investigate sex differences in brain atrophy and cognition in PD de novo patients through MRI subcortical volumetry and cortical thickness (CTh).…
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