Progression of brain atrophy in Parkinson’s disease is shaped by connectome and local vulnerability
Objective: Using MRI data, the aim of this longitudinal study was to map the progression of brain atrophy over four years and relate it to…Safety and efficacy of unilateral subthalamotomy by magnetic resonance guided focused ultrasound (MRgFUS) in asymmetrical Parkinson’s disease (PD).
Objective: To report motor and nonmotor outcomes after unilateral MRgFUS subthalamotomy for the treatment of asymmetrical PD. Background: The development of MRgFUS as a minimally…Using patient-reported quality of life outcomes to assess the validity of smartphone-based remote assessment of motor and cognitive performance in manifest Huntington’s disease patients
Objective: Explore associations between remote monitoring of cognitive and motor functions and digitally administered, self-assessed EuroQol 5-dimension 5-level (EQ-5D-5L) items. Background: Assessment of cognitive and…Deep learning based detection of Parkinson’s disease (PD) in Magnetic Resonance Imaging (MRI) brain scans
Objective: To use a deep learning based framework to classify MRI brain scans as PD or control cases. Background: The Parkinson’s Progression Markers Initiative provides…Brainstem planimetry in Parkinson’s disease with REM behaviour disorder.
Objective: To investigate the association between brainstem planimetry and REM behaviour disorder (RBD) in de novo Parkinson’s disease (PD). Background: RBD is associated with a…First in history MRgFUS treatment procedures remote start and successful treatment of PD patients due to COVID-19 epidemic
Objective: The aim of our study is to present the results of 20 PD patients treated with magnetic resonance guided focused ultrasound thalamotomy (MRgFUS) with…Connectomic Analysis of SNc and VTA Projections to the Striatum and Cortex
Objective: To investigate the dopaminergic neural tracts of healthy individuals using Diffusion MRI on Human Connectome Project Data. Background: Classically, the DA system has been…In-vivo cholinergic basal forebrain degeneration and cognition in Parkinson’s disease: imaging results from the COPPADIS study
Objective: To assess associations between multimodal neuroimaging measures of cholinergic basal forebrain (CBF) integrity and cognition in a well-characterized multicentric cohort of Parkinson’s disease (PD)…The role of network connectivity in shaping the progression of cortical atrophy in Parkinson’s disease
Objective: We aimed to map the progression of cortical thinning and to test whether this pattern is constrained by network connectivity in the brain. Background:…Open-Source Tremor Tracking for MR-guided Focused Ultrasound (MRgFUS): An Objective Approach for Monitoring Treatments
Objective: To describe a novel system developed for real-time noninvasive monitoring of treatment efficacy in patients undergoing MR-guided Focused Ultrasound (MRgFUS) treatment for refractory tremor.…
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