Cognitive flexibility associates with atrophy and disrupted connectivity of the cognitive cerebellum in degenerative cerebellar ataxia
Objective: This study was to investigate the features of cognitive flexibility in patients with degenerative cerebellar ataxia, and to identify the pathophysiological correlates of cognitive…Habenula Volume in Mood Disorders in Parkinson’s Disease
Objective: To assess whether dysregulation of habenula (Hb) contributes to mood disorders in Parkinson’s disease (PD). Background: PD is often accompanied by mood disorders, such…Accelerated longitudinal brain atrophy in the ‘diffuse malignant’ Parkinson’s disease subtype
Objective: To investigate differential pattern of brain atrophy between Parkinson’s disease (PD) clinical subtypes using longitudinally acquired brain magnetic resonance imaging (MRIs). Background: Parkinson’s disease…Leveraging MRI and machine-learning for early detection of cognitive impairment in Parkinson’s disease
Objective: To develop a machine learning model using MRI data that predicts the likelihood of cognitive impairment in newly diagnosed patients with Parkinson's disease (PD).…Contribution of MRI and machine learning approaches to the diagnosis of patients with early-stage parkinsonism in a situation of clinical uncertainty
Objective: To determine whether MRI and machine learning approaches improve diagnostic accuracy in patients with early-stage parkinsonism compared to clinical criteria Background: Parkinson’s disease (PD)…Imaging the noradrenergic system in Parkinson’s disease: A [11C]Yohimbine PET and neuromelanin MRI study
Objective: To assess two aspects of the noradrenergic system using multimodal in vivo imaging in a sample of Parkinson’s disease (PD) patients and healthy controls…Diagnosis of Parkinson’s disease, multiple system atrophy, and progressive supranuclear palsy with 7T-MRI substantia nigra imaging
Objective: To detect the signal change of nigrosome-1 in 7T-MRI and its diagnostic and differential diagnostic efficacy as the imaging biomarker of PD, MSA-P, MSA-C…White matter integrity in patients with PSP-RS and VaP: A TBSS Study
Objective: The purpose of the present study was to compare alterations of brain white-matter microstructure and tissue integrity in PSP-RS and VaP patients using Diffusion…Unique consecutive order of brain atrophy in spinocerebellar ataxia type 3 (SCA3)
Objective: The aim was to identify the sequence of brain regions becoming atrophic in the early phase of spinocerebellar ataxia type 3 (SCA3). Background: SCA3…Neuromelanin related 7T MRI of the locus coeruleus differs between Parkinson’s disease and controls
Objective: To compare the signal intensity of the substantia nigra and locus coeruleus on Magnetization Transfer 7T MRI between PD patients and healthy controls (HC)…
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