Design, characterization and In vivo evaluation of intranasal delivery of levodopa loaded microspere for Parkinsonism
Objective: Levodopa is the drug of choice in the treatment of Parkinson's disease but it exhibits low oral bioavailability and very low brain uptake. The…Sudden alopecia secondary to levodopa treatment
Objective: Report a rarely documented side effect of dopaminergic therapy and review the literature on this aspect, highlighting the underlying mechanisms hypothetically involved. Background: Levodopa…Levodopa response in later stages of Parkinson’s disease: a case-control study
Objective: To compare the response of motor and non-motor symptoms (NMS) to a L-dopa challenge test between late stage (LS) PD patients and advanced stage…Factors associated with dyskinesia in Parkinson’s disease in Mainland China
Objective: To identify the association between dyskinesia and related risk factors, the medication dosage range considered safe and treatment-related variables.To identify the association between dyskinesia…Levodopa-responsive tremor in a young child as a delayed complication of osmotic demyelination from severe hypernatremia
Objective: To describe a case of levodopa responsive tremor due to osmotic demyelination as a result of severe hypernatremia Background: Osmotic demyelination is a known…Opicapone and levodopa-carbidopa intestinal gel infusion: a cost saving analysis in the United Kingdom
Objective: To investigate whether the use of Opicapone as an add-on therapy to levodopa-carbidopa intestinal gel (LCIG) infusion in advanced Parkinson’s disease (PD) reduces the…Effect of gastrointestinal surgery on the pharmacokinetics of levodopa in Parkinson’s disease
Objective: The aim of this study is to evaluate the pharmacokinetics of levodopa in patients with Parkinson’s disease (PD) who underwent gastrointestinal surgery. Background: Levodopa…Long-term effect of levodopa-carbidopa intestinal gel on axial signs in Parkinson’s disease
Objective: To investigate the long-term effect of levodopa-carbidopa intestinal gel (LCIG) on axial signs in Parkinson's disease (PD) patients and the related prognostic factors. Background:…Clinical features of constipation in patients with Parkinson’s disease: a cross-sectional study in China
Objective: This study was designed to explore the clinical features of constipation, and investigate the risk factors of constipation in Chinese PD patients. Background: Constipation…Levocarb-induced diplopia in idiopathic Parkinson’s disease: a case report
Objective: To present a case report of Levocarb-induced diplopia in idiopathic Parkinson’s disease. Background: Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by a…
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