The Roles of Diet, Exercise, & Supplements in Parkinson’s Disease Progression
Objective: The goal of this ongoing study is to describe whether modifiable aspects of lifestyle are associated with PD symptom severity and progression. Background: Epidemiological…Serum soluble transferrin receptor levels correlate with the Hoehn & Yahr stage of Parkinson disease progression
Objective: To test whether levels of soluble transferrin receptor (sTfR) in the serum of Parkinson disease (PD) patients are correlated with the progression of the disease…Alpha-synucleinopathy and mitochondrial dysfunction in a cell based model of neurodegeneration: Implications in the pathogenesis of sporadic Parkinson’s disease
Objective: To elucidate the role of α-synuclein, parkin and mitochondria in a cell-based model of neurodegeneration relevant to Parkinson's disease pathogenesis. Background: The suggested mechanisms…Alpha-synuclein protein homeostasis and oligomerization in iron-overloaded cells expressing mutant HFE
Objective: Study the direct and indirect effects of iron overload on alpha synuclein homeostasis in a genetic model of hemochromatosis (HFE) Background: Parkinson’s disease (PD)…Dystonia due to bilateral caudate hemorrhage associated with a COL4A1 mutation
Objective: Pathogenic mutations of COL4A1 are associated with young-onset stroke and porencephaly. We present a case of a 32-year-old female patient with juvenile onset right hand…Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson’s disease
Objective: To employ a combination of elemental concentrations in the cerebrospinal fluid (CSF) to identify a diagnostic biomarker profile differentiating patients with idiopathic Parkinson´s disease…High-Pass Filtered Phase MR Imaging to Detect Longitudinal Motor Associations of Iron Accumulation in Parkinson’s Disease
Objective: To assess whether longitudinal changes in deep grey matter nuclei iron content are associated with declining motor function in Parkinson’s disease over a period…Bristle hair may point to hereditary spastic paraplegia type SPG35/ FAHN
Objective: Finding new phenotypic features or biomarkers in hereditary spastic paraplegia type SPG35 / Fatty Acid Hydroxylase-associated Neurodegeneration (FAHN) to help clinicians to identify this…Phosphorylation by GSK-3β enhances binding of metal ion induced tau oligomers to neutral lipid surfaces
Objective: To dissect the complex interplay of tau hyperphosphorylation, metal ion induced oligomer formation and membrane interactions applying single particle fluorescence techniques. Background: Fibrillar deposits…Relationship of serum ferritin level and tic severity in children with Tourette syndrome
Objective: Evaluate the relationship between serum ferritin levels and tic severity, as well as consequent impact on life, in children with Tourette Syndrome. Background: There…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.