Using quantitative susceptibility mapping and diffusion magnetic resonance imaging to identify structural features of early-stage Parkinson’s disease
Objective: To identify an imaging diagnostic biomarker of PD for use in clinics by applying structural magnetic resonance imaging (MRI) techniques. Background: The midbrain dopaminergic…Quantitative susceptibility mapping of basal ganglia and related structures: correlation with disease severity in Progressive Supranuclear Palsy
Objective: We examined whether magnetic susceptibility estimates from deep gray matter structures in patients with Progressive Supranuclear Palsy (PSP) correlated with clinical measures of disease…Apathy in Parkinson’s disease: serum biochemical markers and clinical features
Objective: This study aims to explore clinical features and blood biochemical markers of apathy in PD. Background: Apathy is one of the most common non-motor…Epidemiological, clinical and paraclinical characteristics of metals accumulation in brain in childhood
Objective: The aim of our study is to describe epidemiological, clinical, and paraclinical characteristics of metals accumulation in brain in children. Background: Movement disorders can…Quantitative susceptibility mapping images for the parcellation of the Subthalamic Nucleus: a possible role for targeting Deep Brain Stimulation
Objective: To investigate the iron distribution in STN in PD patients using QSM images. Background: Subthalamic Deep Brain Stimulation (DBS) is considered an effective treatment…Elevated nigral iron is associated with low plasma serotonin in Parkinson’s disease
Objective: The objective of this work was to determine whether plasma serotonin levels in Parkinson’s disease (PD) are related to iron levels in the brain,…Visualization of Nigrosome 1 at 3T MRI and 18F-DOPA PET for the diagnosis of Parkinson´s disease
Objective: To determine and compare the utility of Nigrosome 1 at 3T MRI and 18F-DOPA PET for the diagnosis of Parkinson´s disease. Background: Differential diagnosis…Quantification of regional iron content with Susceptibility Weighted Imaging in Huntington Disease Expansion Gene Carriers
Objective: To assess brain iron content measured with SWI-MRI in HD gene expansion carriers (HDGECs). Background: Huntington’s Disease (HD) results in extensive neuronal cell loss,…Safety of Iron Chelation in Patients with Brain Iron Overload
Objective: To assess the safety of iron chelation in the treatment of regional brain iron overload. Background: Excess brain iron is evident in neurodegenerative diseases…Iron Supplementation for the Treatment of Restless Legs Syndrome – A Systematic Review and Meta-Analysis
Objective: To gather the evidence for the efficacy and safety of iron supplementation for restless legs syndrome (RLS). Background: Iron supplementation is used for the…