The Intention Component of Postural Tremor in Essential Tremor
Objective: This study seeks to better characterize postural tremor in ET and to investigate the effect of intention and visual input on the amplitude and…Brain-behavior quantification and synchronization to drive closed-loop deep brain stimulation
Objective: Closed-loop DBS systems require a neural biomarker to responsively turn on stimulation, which in turn requires neurophysiological quantification synchronized to behavior or symptoms. Our…Focused ultrasound offers tremor relief in multiple system atrophy patients
Objective: To report on the efficacy and safety of MRI-guided focused ultrasound (FUS) VIM-thalamotomy in patients with multiple system atrophy (MSA). Background: FUS has established…Levodopa-responsive tremor in a young child as a delayed complication of osmotic demyelination from severe hypernatremia
Objective: To describe a case of levodopa responsive tremor due to osmotic demyelination as a result of severe hypernatremia Background: Osmotic demyelination is a known…Novel Mutation of NUS1 Gene Presenting With Developmental And Epileptic Encephalopathy and Movement Disorders
Objective: To report the range of movement disorders associated with a NUS1 gene mutation. Background: To date, pathogenic loss-of-function de novoNUS1mutations have been described in only…Adult-onset neuronal intranuclear inclusion disease presenting with intractable resting and intention tremor
Objective: To report a rare case of neuronal intranuclear inclusion disease (NIID) presenting with intractable resting and intention tremor. Background: The NIID is a slowly…The spectrum of involuntary movements in patients with motor neuron disease – a cross-sectional study
Objective: To describe prevalence, clinical characteristics and electrophysiological findings of involuntary movements in patients with motor neuron disease (MND). Background: Involuntary movements are not considered…Towards a responsive deep brain stimulation for the treatment of essential tremor
Objective: To identify neurophysiologic markers of intention tremor in the ventral intermediate thalamic nucleus (Vim) and hand motor cortex to develop closed-loop deep brain stimulation…