Type 2 diabetes mellitus may worsen severity of motor symptoms in people with Parkinson’s disease
Objective: We aimed to determine whether co-morbid type 2 diabetes mellitus (T2DM) would impact the motor or non-motor symptom severity in people with Parkinson’s (PwP).…Unraveling the role of amylin oligomers in synucleinopathies
Objective: The aim of this work is to elucidate the role of amylin in both alpha-synuclein amyloid formation and Parkinson’s disease (PD) and dementia with…Metabolic syndrome and insulin resistance in Parkinson’s disease: could they affect motor or cognitive symptoms?
Objective: The objective of this work was to detect the markers of metabolic syndrome and insulin resistance in patients with PD and to study their…Role of metformin in diabetic aging female rat brain: a future therapy for neurodegenerative diseases
Objective: The objective of this study was to investigate effects of metformin on glucose transporter (GLUT1, GLUT3) expression, intracellular calcium levels, expression of synaptic molecules…The course of Parkinson’s disease in patients with impaired carbohydrate metabolism
Objective: To study the state of lipid metabolism in PD patients with concomitant type 2diabetes (with different glucose tolerance and the effect of DA agonist…Intranasal delivery of insulin for the restoration of memory signaling in Alzheimer disease
Objective: Objective of this study is to develop delivery-system to overcome BBB by employing novel, non-invasive approach via nasal route. Background: Alzheimer's disease(AD), a form…Diabetes Mellitus Alters Resting State Functional Networks in Early-Stage Parkinson’s Disease without Dementia
Objective: The purpose of this study was to evaluate the alterations of five major resting state networks (RSNs) and striatum-related functional connectivity (FC) in early-stage…Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synuclenopathies
Objective: We have investigated whether deposits of phosphorylated α-synuclein might be present in pancreatic tissue of subjects with synucleinopathies. Background: Parkinson’s disease patients experience a…Diabetes Mellitus and Parkinson’s Disease
Objective: To investigate the association of type 2 diabetes mellitus (DM) with markers of Parkinson’s pathology in patients with early de novo Parkinson’s disease (PD).…Disease progression and clinical characteristics of Parkinson’s disease patients with type 1 diabetes – An analysis on 18,162 patients from the DPV registry
Objective: To determine if type 1 diabetes (T1DM) mellitus patients with Parkinson's disease (PD) exhibit similar characteristics of disease progression as T1DM patients without PD.…