Non-invasive Vagus Nerve Stimulation Alters Molecular Markers in Parkinson’s Disease Patients with Freezing of Gait
Objective: To investigate molecular mechanisms underlying non-invasive vagus nerve stimulation (nVNS) in Parkinson’s disease (PD) patients with freezing of gait (FOG). Background: FOG remains one…Therapeutic effects of citral nanoliposome on Parkinson’s treatment in a rat model: Modulation via neurochemical, inflammatory and antioxidant pathways
Objective: The present study aimed to assess the effects of citral nanoliposome on Parkinson's treatment in a rat model. Background: Parkinson's disease is the most…Serum levels of IL-1β and interleukin 6 in Parkinson’s disease
Objective: We aim to assess IL-1 β and IL-6 serum levels in patients with PD and in controls and to explore their associations with clinical…LRRK2 G2019S promotes astrocytic inflammatory response induced by oligomeric α-synuclein through NF-κB pathway
Objective: Analyzing the mechanism of inflammatory response induced by oligomeric α-synuclein (O-αS) in LRRK2 G2019S mutation astrocytes to provide new targets and ideas for the…Associations of IL-1β and IL-6 gene polymorphisms with Parkinson’s disease(PD)
Objective: We aim to explore the associations of IL-1β and IL-6 gene polymorphisms with the pathogenesis of PD and with clinical features of motor and…Honey prevented MPTP-induced oxidative stress, neuroinflammation and gliosis in adult male Swiss mice.
Objective: To investigate the neuroprotective role of honey against oxidative stress and neuroinflammation induced by MPTP in adult male Swiss mice. Background: Oxidative stress and…Inflammatory biomarkers in newly diagnosed patients with Parkinson’s disease
Objective: To identify a panel of cerebrospinal fluid (CSF) inflammatory biomarkers for Parkinson’s disease (PD) and to compare levels of inflammatory proteins in control subjects…SCFAs participate in the pathogenesis of Parkinson’s disease by regulating NLRP3 inflammasomes activation
Objective: To explore the role and related mechanism of gut microbiota metabolites short-chain fatty acids(SCFAs) in the pathogenesis of Parkinson's disease(PD). Background: Growing research have…Multi-modal prognostic biomarkers for Parkinson’s disease progression and severity
Objective: To determine a pathophysiological panel of biomarkers significantly associated with the severity and the disease progression of Parkinson’s disease. Background: Detecting, monitoring and predicting…Dried blood and plasma spots for the measurement of neurofilament light chain and inflammatory cytokines in patients with REM sleep behaviour disorder
Objective: The objective of this study was to investigate the relationship between plasma and dried blood/ plasma spot measurements of inflammatory markers (IFN-ɣ, IL-1β, IL-6,…
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