Immune-Mediated and Mercury Intoxication Ataxias: Anti-GAD Antibodies and Dynamic Stabilometriс Assessment
Objective: The goals of our study were evaluation of disequilibrium, static and dynamic functions and anti-GAD antibodies concentrations in immune mediated and mercury intoxication ataxias…SARS-CoV-2 Encephalopathy Presenting as Opsoclonus Myoclonus Syndrome Successfully Treated with IV Immunoglobulins
Objective: To present a case of a SARS-CoV-2 patient presenting with opsoclonus myoclonus syndrome who was successfully treated with IVIGs. Background: The COVID-19 pandemic has…Cytokines and Brain Specific Antibodies in Experimental Cellular and Molecular Treatment of Huntington’s Diseases
Objective: Huntington’s Disease (HD) is a severe neurodegenerative disorder main pathogenic factor is CAG repeats in a suffered patients genome. Experimental therapy on the model…The clinical spectrum of movement disorders associated with neuronal antibodies
Objective: To describe the clinical and treatment characteristics of movement disorders associated with antibodies (Abs) against neuronal synaptic extracellular (NMDAR, LGI1, CASPR2, IgLON5, Glycine receptors…A case of cerebellar ataxia caused by Pembrolizumab for Non-small cell lung cancer
Objective: We reported a case that cerebellar ataxia and decreased accumulation of right cerebellum at SPECT appeared after immunotherapy using immune-checkpoint inhibitor “Pembrolizumab” for Non-small…Gluten sensitivity in progressive cerebellar ataxia patients from India
Objective: To screened a well-defined cohort of patients with cerebellar ataxia for the presence of gluten sensitivity. Background: Cerebellar ataxia is a heterogeneous group of…mGluR1 antibodies encephalitis: A rare cause of reversible ataxia and myoclonus syndrome
Objective: We wanted to report the case of a patient with severe subacute cerebellar ataxia related to mGluR1-antibodies with a clear improvement after immunomodulator treatment.…Antibodies to alpha-Synuclein in Parkinson disease
Objective: Alpha-synuclein (α-syn) plays a very important role in pathogenesis of Parkinson’s disease (PD). There are enough evidence of neuroinflammation in the brain tissue of…Natural occurring antibodies reduce aggregation of α-synuclein
Objective: We tested naturally occurring antibodies (nAbs) against α-synuclein both in vitro as well as in HEK293T cells to determine binding, cell viability and capacity…Design and Status of the BIIB054 SPARK Trial
Objective: To describe the design and status of the BIIB054 SPARK trial of the safety and potential efficacy of a monoclonal antibody (mAb) targeting alpha-synuclein…