MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Huntingtons disease"

  • 2016 International Congress

    Verbatim patient-reported outcomes and trails making test B (TMT-B) performance in the REACH2HD trial

    J.L. Purks, A. Zeymo, N.M. Shara, K.E. Anderson, I. Shoulson (Washington, DC, USA)

    Objective: Examine the relationship between Trails Making Test B (TMT-B) performance and bothersome cognitive complaints among Huntington Disease (HD) research participants in the REACH2HD randomized-controlled…
  • 2016 International Congress

    Enroll-HD: A global clinical research platform for Huntington’s disease

    T.A. Mestre, C. Fitzer-Attas, J. Giuliano, B. Landwehrmeyer, C. Sampaio (Ottawa, Canada)

    Objective: To provide an update on the global observational registry study of Huntington's disease (HD) included in Enroll-HD, a platform for HD clinical research. Background:…
  • 2016 International Congress

    A randomized, double-blind, placebo-controlled trial of deutetrabenazine for the treatment of tardive dyskinesia (ARM-TD)

    H.H. Fernandez, S.A. Factor, R.A. Hauser, J. Jimenez-Shahed, W. Ondo, M.S. LeDoux, D. Shprecher, T. Simuni, D. Stamler, K.E. Anderson (Cleveland, OH, USA)

    Objective: To determine the efficacy and safety of deutetrabenazine (DTB) as a treatment for tardive dyskinesia (TD). Background: There is no approved treatment for TD,…
  • 2016 International Congress

    Cortico-striatal functional connectivity in the premanifest and manifest period of Huntingtons disease measured with high-field functional magnetic resonance imaging

    M. Kronenbuerger, J. Hua, C.A. Ross (Baltimore, MD, USA)

    Objective: To assess functional connectivity in the premanifest and manifest period of Huntington's disease (HD) by using functional Magnetic Resonance Imaging (fMRI) at high-field (7…
  • 2016 International Congress

    Specific in-patient’s rehabilitation improves postural and gait instability in Huntington’s disease

    L. Brabcová, J. Roth, O. Horácek, M. Kolárová, H. Bozková, J. Rusz, P. Košková, K. Lísalová, F. Jancok, J. Klempír, E. Ruzicka, H. Brozová (Beroun, Czech Republic)

    Objective: To evaluate long-term effects of targeted rehabilitation on postural and gait stability in the early and middle stages of Huntington disease (HD). Background: HD…
  • 2016 International Congress

    A pilot study of SD-809 (deutetrabenazine) in tics associated with Tourette syndrome

    J. Jankovic, J. Jimenez-Shahed, C. Budman, B. Coffey, T.K. Murphy, D. Shprecher, D. Stamler (Houston, TX, USA)

    Objective: This study explored the safety, tolerability and preliminary efficacy of SD-809 (deutetrabenazine) in adolescents with moderate to severe tics associated with Tourette syndrome (TS).…
  • 2016 International Congress

    Striatal molecular alterations in Huntington’s disease gene expansion carriers: A systematic review and meta-analysis of PET studies

    F. Niccolini, G. Pagano, P. Fusar-Poli, A. Wood, L. Mrzljak, C. Sampaio, M. Politis (London, United Kingdom)

    Objective: To systematically examine the evidence of striatal molecular alterations in premanifest and manifest Huntington's disease gene expansion carriers (HDGECs) as measured by Positron emission…
  • 2016 International Congress

    Epidemiology and economic burden of falls and fractures in patients with Huntington’s disease

    D.O. Claassen, P. Donga, S. Rajagopalan, L.M. De Boer, B. Carroll, S. Gandhi (Nashville, TN, USA)

    Objective: To assess epidemiology and economic burden of falls and fractures among Huntington's disease (HD) patients. Background: The clinical course of HD is characterized by…
  • 2016 International Congress

    Evidence of striatal dopaminergic dysfunction Sydenham’s chorea in remission with (99m)Tc-TRODAT-1 SPECT

    R. Maciel, D. Maia, C.F. de Lima, F. Cardoso (Belo Horizonte, Brazil)

    Objective: To report the findings of reduced striatal dopamine transporter (DAT) density in patients with Sydenham's chorea (SC) in remission assessed by single-photon emission computed…
  • 2016 International Congress

    Tau pathology in Huntington’s disease: A brief in vivo PET-imaging report

    K. Giehl, K. Reetz, I. Dogan, C. Werner, J.B. Schulz, A. Drzezga, T. van Eimeren (Köln, Germany)

    Objective: To assess feasibility of measuring pathological tau deposition in patients with Huntington's disease (HD) using [18F]-AV-1451 (f.k.a. T807) PET. Background: HD is a progressive…
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