Increased Resting Anterior Hippocampus Metabolism and Hippocampus Subfields Structural Abnormalities in Functional Tremor Patients: FDG- PET Study and Volumetric MRI Study
Objective: In this study, we focused on identifying the resting 18F-FDG PET brain imaging patterns in the limbic region and measuring the MRI volumes of…Neuroprotective Efficacy of Ethanolic Extract from Amorphophallus Paeoniifolius Tuber Against Haloperidol-Induced Parkinson’s Disease Model
Objective: This study aimed to evaluate the neuroprotective and antiparkinsonian effects of the ethanolic extract of Amorphophallus paeoniifolius tuber (APT) against haloperidol-induced Parkinson’s Disease (PD)…Hippocampal volume in Parkinson’s Disease in south India
Objective: To analyse hippocampal volume differences among the patients with Parkinson’s disease and healthy individuals. Background: In humans, hippocampus is involved in regulation of emotions,…Polyaromatic hydrocarbons in Ambient Particulate Matter (PM 2.5) mediate neurodegeneration through the olfactory-brain axis in C57BL/6 mice
Objective: To delineate the molecular mechanisms involved in bidirectional olfactory-brain-induced neurodegeneration caused by exposure to ambient particulate matter (PM2.5). Background: Air pollution has been linked…Association between changes in hippocampal volumes, cognition, and CSF markers in Parkinson’s Disease
Objective: To assess whether changes in hippocampal subfield volumes are associated with cognition or CSF β-amyloid 1–42 (Aβ42) levels in Parkinson’s Disease (PD). Background: Hippocampal…T1 MRI reveals differential hippocampal atrophy in Lewy body disorders with and without Alzheimer’s copathology
Objective: Determine whether MRI can identify differences in hippocampal volume between patients with Lewy body disorders with and without Alzheimer's copathology, and whether these differences…Melatonin attenuates the bidirectional Gut-Brain axis mediated inflammation caused by Ambient Particulate Matter (PM2.5) and averts neurodegeneration
Objective: To explore the therapeutic potential of melatonin in attenuating the PM2.5 induced inflammation and neurodegeneration through the Gut-brain axis in C57BL/6 mice. Background: The…Fibrinogen and CFAH: The two putative markers of Parkinson’s disease with cognitive impairment
Objective: To determine the pathogenic potential of fibrinogen and complement factor H (CFAH) in causing Parkinson’s disease (PD) with cognitive impairment (PDCI)-like symptoms using C57BL/6J…Therapy to Reduce dementia risk In Parkinson’s disease (TRIP): Proof-of-concept trial
Objective: The TRIP proof-of-concept study examines functioning of the hippocampal DG/CA3 subregion as a biomarker and therapeutic target for memory impairment in Parkinson’s Disease (PD).…Association between Hippocampal Subfields, CSF Biomarkers, and Cognition in non-demented Parkinson’s patients
Objective: To determine whether hippocampal subfield volumes in non-demented Parkinson’s Disease (PD) are primarily predicted by cognition or CSF β-amyloid 1–42 (Aβ42) levels. Background: The…