Use of insect model to study Parkinson’s disease pathophysiology by inducing GSH-depletion and behavioral deficits among larvae: Evidences of ameliorative properties of phytoconstituents
Objective: The purpose of the study is to establish an all-around model for Parkinson's disease using Drosophila melanogaster, the fruit-fly in order to understand behavioral…Association Between Over-the-Counter Dietary Supplements and Parkinson’s Disease Symptom Severity Over Time
Objective: The goal of this study was to evaluate whether the use of nutraceuticals and dietary supplements are associated, on a population level, with Parkinson’s…Mutational effects of LRRK2 I1371V in astrocytes derived from patient specific iPSCs
Objective: To identify the LRRK2 I1371V mutational effects on astroglial biology involving glutamate metabolism and glutathione machinery. Background: The underlying cause of most of the familial…Differential glial and neuronal response in Lipopolysaccharide induced Parkinson’s disease model: Modulation with Apocyanin and Curcumin
Objective: To understand the differential susceptibility of neuronal and glial populations to lipopolysaccharide (LPS) mediated insult in an animal model of PD. Also, to test…The Roles of Diet, Exercise, & Supplements in Parkinson’s Disease Progression
Objective: The goal of this ongoing study is to describe whether modifiable aspects of lifestyle are associated with PD symptom severity and progression. Background: Epidemiological…Vagus nerve stimulation as a novel treatment strategy for Parkinson’s disease
Objective: To assess the therapeutic potential of chronic vagus nerve stimulation (VNS) to attenuate the behavioral and neuronal deficits observed in Parkinson's disease (PD) by…Glutathione status in Parkinson’s disease
Objective: Describe measures of glutathione (GSH) status in a cohort of individuals with Parkinson's disease (PD). Background: It is well established that redox stress contributes…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.