GAD-Positive Versus GAD-Negative Stiff Person Syndrome: A Retrospective Study
Objective: Delineate demographic and clinical differences between GAD-65-antibody positive (seropositive) and negative (seronegative) SPS. Background: Elevated Glutamic Acid Decarboxylase 65 antibody (GAD-65 Ab) titers are…Anti-glutamic acid decarboxylase associated encephalitis presenting with new onset movement disorder after COVID-19 infection
Objective: To describe the unusual clinical manifestations in a patient with coronavirus disease 2019 (COVID-19). Background: Movement disorders are uncommon neurological manifestations of severe acute…Stiff person syndrome vs functional neurological disorder: two patients with hyperkinetic movement disorder
Objective: To describe two hyperkinetic disorders with manifestations that support the description of stiff-person syndrome Background: Stiff-person syndrome (SPS) is a rare condition with just…Unilateral Hypertrophic Olivary Degeneration in Anti-GAD-associated Encephalomyelitis
Objective: We present a patient with GAD65-Ab-related encephalomyelitis who developed unilateral hypertrophic olivary degeneration (HOD) in the absence of structural lesions within the Guillain-Mollaret triangle.…Outcomes of Gene therapy and Subsequent Deep Brain Stimulation for Parkinson’s Disease
Objective: The purpose of this study is to determine the outcomes of patients who received GAD gene therapy treatment and subsequently underwent DBS for Parkinson’s…Immune-mediated movement disorder as a Rare Manifestation of a Sarcoma
Objective: We describe a rare case of a young woman with an immune-mediated movement disorder (paraneoplastic Stiff Person Syndrome) associated with a mediastinal liposarcoma. This…GAD65 antibody neurologic syndrome presenting with hemiparkinsonism
Objective: To describe a novel phenotype of glutamic acid decarboxylase-65 (GAD65) antibody-associated neurological disease in which an older patient initially presented with levodopa-unresponsive hemiparkinsonism and…Association between Glutamic Acid Decarboxylase Antibodies (Anti-GADs) and Parkinsonism: Case Report
Objective: To make the first case report of the association between Anti-GAD and parkinsonism. Background: GAD (Glutamic Acid Decarboxylase) is the enzyme that catalyzes the synthesis of the…Stiff Limb Syndrome Masquerading As a Focal Limb Dystonia
Objective: To report a case of immune-mediated stiff limb syndrome referred for extremity focal dystonia. Background: Autoantibodies to glutamic acid decarboxylase (GAD) are associated with…Oculopalatal tremor (OPT) in a patient with anti-GAD brainstem encephalitis: A case report
Objective: To report a case of OPT as consequence of anti-GAD brainstem encephalitis Background: OPT is caused by insult to the Guillain-Mollaret triangle. Common etiologies…