A Randomized, Double-Blind, Placebo-Controlled Trial of a Multi-Strain Probiotic for Anxiety in Parkinson’s Disease
Objective: To evaluate the effect of a multi-strain probiotic on anxiety in patients with Parkinson’s disease (PD). Background: There is a lack of dedicated randomized…Therapeutic restoration of Faecalibacterium prausnitzii in Parkinson’s disease using targeted fructoligosaccharides: a double-blind, placebo-controlled, cross-over trial
Objective: In this study, we evaluated the effect of targeted fructoligosaccharide (FOS) therapy to restore the beneficial butyrate producer Faecalibacterium prausnitzii, one the most highly reduced…Gut Microbiota May Alter Glucose Metabolism in Patients with Parkinson’s Disease
Objective: To compare the gut microbiota in patients with Parkinson’s disease (PD) and healthy controls and predict the functional pathways associated with these differences. Background:…Altered gut microbiota composition and metabolism in Parkinson’s disease
Objective: To define changes in gut microbiota composition and metabolism to enable identification of novel therapeutic targets and strategies for disease modification. Background: Multiple cohort…Exploring the Influence of Gastrointestinal Symptoms on Non-Motor Fluctuations in Parkinson’s Disease: Insights from the ReMePark-2, a Mexican Cohort
Objective: To determine the impact of gastrointestinal symptoms on NMF in PD among Mexican individuals living with PD (PwP). Background: The growing interest in the…The Effect of an Exogenous Ketone Supplement on Gut Microbiota in Parkinson’s disease, a Pilot Study
Objective: To investigate the effect of exogenous oral ketone esters on gut microbiota in people with PD. Background: Mitochondrial dysfunction in the substantia nigra and…Molecular Landscape of Gastrointestinal Dysfunctions in Parkinson’s Disease
Objective: Analyze multi-omics data from the PPMI cohort to identify molecular markers associated with self-reported gastrointestinal (GI) dysfunction in Parkinson's disease (PD) patients. Background: PD…Comparison of Gastrointestinal Dysfunction in Early-onset and Late-onset Parkinson’s Disease
Objective: To compare the gastrointestinal dysfunction in patients with early-onset Parkinson’s disease (EOPD) and late-onset Parkinson’s disease (LOPD). Background: Gastrointestinal dysfunction is one of the…Gastrointestinal Dysbiosis and Clinical Outcomes in Parkinson’s Disease
Objective: To evaluate whether patients with PD exhibit 1) a bloom in sulfate-reducing bacteria based on the detection of hydrogen-sulfide (H2S) during lactulose breath testing…Beyond constipation: gastrointestinal phenomena in Parkinson’s disease
Objective: To describe the prevalence of gastrointestinal manifestations in patients with Parkinson's disease in a Brazilian movement disorders outpatient clinic and evaluate their associated factors…
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