A Phase 2 Randomized Clinical Trial of TAK-071, an Acetylcholine M1 Receptor Positive Allosteric Modulator, in Parkinson Disease with Cognitive Impairment
Objective: To study the safety and efficacy of TAK-071, an M1 positive allosteric modulator, in adults with Parkinson disease (PD) with increased risk for falls…Effects of Mental Practice on FOG in People with Parkinson’s Disease: a Randomized Clinical Trial
Objective: To compare the effects of an experimental intervention (EI) based on NCI with a control intervention (CI) of equal volume and intensity, differing only…Effect of Tactile Cueing on Dual Task Performance in Parkinson’s Disease-A Systematic Review and Meta-Analysis
Objective: This systematic review and meta-analysis were performed to examine the effect of tactile cueing on dual task (DT) performance in adults with idiopathic Parkinson’s…Exploring Non-Invasive Wearable Devices in Home Settings for Assessment and Treatment of the Duration of ON and OFF State and Freezing of Gait in Parkinson’s Disease: A Case Study.
Objective: To assess the effect of cueing with vibrotactile stimulation on the duration of ON and OFF state and freezing of gait (FOG) in patients…Studying digenic Parkinson’s disease in a stem cell model carrying mutant p.N409S in the GBA1 gene and the homozygous deletion of exon 3 PARK2
Objective: We aim to study the combined effect of the GBA1 p.N409S mutation and a complete loss of Parkin based on a patient-based stem cell…MRI Predictive Marker of the Vestibular Galvanic Stimulation Effectiveness in the Postural Instability Treatment in Parkinson’s Disease.
Objective: To assess the galvanic vestibular stimulation (GVS) effect on axial symptoms and cervical vestibular evoked myogenic potential (cVEMP) depending on the Magnetic Resonance Parkinsonism…Focused Ultrasound Therapy Treatment for Parkinson’s Disease
Objective: Parkinson’s Disease is a neurodegenerative disease that mainly affects the substantia nigra and nigrostriatal pathway and leads to rigidity, loss of muscle tone, tremors,…Clinical and Imaging Changes in Parkinson’s Disease Patients Under Spinal Cord Stimulation: A Double Blinded Analysis
Objective: Evaluate clinical and biomarker changes from spinal cord stimulation (SCS) in Parkinsons Disease (PD) under sham controlled randomized evaluation. Background: SCS has been proposed…Split-belt Treadmill Training to Rehabilitate Freezing of Gait and Balance in Parkinson’s Disease
Objective: Can repeated exposure to a split-belt treadmill (SBTM) encourage motor learning to improve freezing of gait (FOG) and reduce the number of falls in…Wearable Device for Real-Time Prevention of Freezing-of-Gait in Parkinson’s Disease
Objective: In our previous work, we developed machine learning models to predict and detect freezing-of-gait (FOG) [1]. In this study, we aimed to use those…
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